The Effect of the Intelligent Sepsis Management System on Outcomes among Patients with Sepsis and Septic Shock Diagnosed According to the Sepsis-3 Definition in the Emergency Department
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Song, Juhyun | - |
dc.contributor.author | Cho, Hanjin | - |
dc.contributor.author | Park, Dae Won | - |
dc.contributor.author | Ahn, Sejoong | - |
dc.contributor.author | Kim, Joo Yeong | - |
dc.contributor.author | Seok, Hyeri | - |
dc.contributor.author | Park, Jonghak | - |
dc.contributor.author | Moon, Sungwoo | - |
dc.date.accessioned | 2021-09-01T00:53:01Z | - |
dc.date.available | 2021-09-01T00:53:01Z | - |
dc.date.created | 2021-06-19 | - |
dc.date.issued | 2019-11 | - |
dc.identifier.issn | 2077-0383 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/61972 | - |
dc.description.abstract | We developed a novel computer program, the Intelligent Sepsis Management System, based on Sepsis-3 definitions and 2016 Surviving Sepsis Campaign guidelines and performed a quasi-experimental pre-post study to assess its effect on compliance with the Surviving Sepsis Campaign guidelines and outcomes in patients with sepsis and septic shock. During the pre-period, patients were managed with usual care. During the post-period, patients were managed using the Intelligent Sepsis Management System upon arrival at the emergency department. A total of 631 patients were enrolled (pre-period, 316; post-period, 315). The overall compliance with the Surviving Sepsis Campaign guidelines' bundle improved (pre-period 10.8% vs. post-period 54.6%; p < 0.001). The post-period showed significantly lower 30-day mortality than the pre-period (pre-period 37.3% vs. post-period 29.5%; p = 0.037), but was not a protective factor for 30-day mortality, with an adjusted hazard ratio (95% confidence interval) of 0.75 (0.55-1.04) (p = 0.151). The associated factors for 30-day mortality were age, sequential organ failure assessment score, overall compliance, and lactate levels. The 30-day mortality was significantly lower in the compliance group than in the non-compliance group (27.2% vs. 36.5%; p = 0.002). After implementation of the Intelligent Sepsis Management System, overall compliance with the Surviving Sepsis Campaign guidelines improved and was associated with reduced 30-day mortality. However, we could not verify the causal effect of this system on 30-day mortality. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | MDPI | - |
dc.subject | INTERNATIONAL CONSENSUS DEFINITIONS | - |
dc.subject | GOAL-DIRECTED RESUSCITATION | - |
dc.subject | CLINICAL-CRITERIA | - |
dc.subject | RANDOMIZED-TRIAL | - |
dc.subject | INTENSIVE-CARE | - |
dc.subject | MORTALITY | - |
dc.subject | PROGRAM | - |
dc.title | The Effect of the Intelligent Sepsis Management System on Outcomes among Patients with Sepsis and Septic Shock Diagnosed According to the Sepsis-3 Definition in the Emergency Department | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Song, Juhyun | - |
dc.contributor.affiliatedAuthor | Cho, Hanjin | - |
dc.contributor.affiliatedAuthor | Park, Dae Won | - |
dc.contributor.affiliatedAuthor | Seok, Hyeri | - |
dc.contributor.affiliatedAuthor | Park, Jonghak | - |
dc.identifier.doi | 10.3390/jcm8111800 | - |
dc.identifier.wosid | 000502294400043 | - |
dc.identifier.bibliographicCitation | JOURNAL OF CLINICAL MEDICINE, v.8, no.11 | - |
dc.relation.isPartOf | JOURNAL OF CLINICAL MEDICINE | - |
dc.citation.title | JOURNAL OF CLINICAL MEDICINE | - |
dc.citation.volume | 8 | - |
dc.citation.number | 11 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | General & Internal Medicine | - |
dc.relation.journalWebOfScienceCategory | Medicine, General & Internal | - |
dc.subject.keywordPlus | INTERNATIONAL CONSENSUS DEFINITIONS | - |
dc.subject.keywordPlus | GOAL-DIRECTED RESUSCITATION | - |
dc.subject.keywordPlus | CLINICAL-CRITERIA | - |
dc.subject.keywordPlus | RANDOMIZED-TRIAL | - |
dc.subject.keywordPlus | INTENSIVE-CARE | - |
dc.subject.keywordPlus | MORTALITY | - |
dc.subject.keywordPlus | PROGRAM | - |
dc.subject.keywordAuthor | emergency department | - |
dc.subject.keywordAuthor | mortality | - |
dc.subject.keywordAuthor | sepsis | - |
dc.subject.keywordAuthor | septic shock | - |
dc.subject.keywordAuthor | Surviving Sepsis Campaign guidelines | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(02841) 서울특별시 성북구 안암로 14502-3290-1114
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.