Effect of Pre-Procedural Beta-Blocker on Clinical Outcome after Percutaneous Coronary Intervention in Acute Coronary Syndrome From the 2014 K-PCI Registry
DC Field | Value | Language |
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dc.contributor.author | Kim, Bum Sung | - |
dc.contributor.author | Eom, Sang-Youg | - |
dc.contributor.author | Kim, Sung Hea | - |
dc.contributor.author | Hwang, Hweung Kon | - |
dc.contributor.author | Park, Jong-Seon | - |
dc.contributor.author | Kim, Weon | - |
dc.contributor.author | Lee, Jun-Won | - |
dc.contributor.author | Rha, Seung-Woon | - |
dc.contributor.author | Kim, Geon Young | - |
dc.contributor.author | Lim, Sang Wook | - |
dc.contributor.author | Lee, Su Hun | - |
dc.contributor.author | Chae, Jei Keon | - |
dc.contributor.author | Woo, Seong-Ill | - |
dc.contributor.author | Bae, Jang-Whan | - |
dc.contributor.author | Kim, Hyun-Joong | - |
dc.date.accessioned | 2021-09-01T01:13:38Z | - |
dc.date.available | 2021-09-01T01:13:38Z | - |
dc.date.created | 2021-06-19 | - |
dc.date.issued | 2019-11 | - |
dc.identifier.issn | 1349-2365 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/61995 | - |
dc.description.abstract | The efficacy of pre-procedural beta-blocker use in patients with acute coronary syndrome (ACS) is not well established in the current percutaneous coronary intervention (PCI) era. We investigate the effect of preprocedural beta-blocker use on clinical outcomes in patients with ACS undergoing PCI. Among 44,967 consecutive cases of PCI enrolled in the nationwide, retrospective, multicenter registry (K-PCI registry), 31,040 patients with ACS were selected and analyzed. We classified patients into pre-procedural beta-blocker group (n = 8,678) and pre-procedural no-beta-blocker group (n = 22.362) according to the use of beta-blockers at least for two weeks before index PCI. Propensity score-matching analysis was performed and resulted in 7,445 pairs. The primary outcome was in-hospital cardiac death. In propensity score-matched populations, the pre-procedural beta-blocker group had a lower incidence of in-hospital cardiac death compared with the pre-procedural nobeta-blocker group (1.1% versus 2.0%, unadjusted odds ratio [OR]: 0.56, 95% confidence interval [CI]: 0.420.73, P < 0.01). In subgroup analysis. the pre-procedural beta-blocker group had a lower incidence of inhospital cardiac death, compared with the pre-procedural no-beta-blocker group in ST-segment elevation myocardial infarction subpopulation (3.1% versus 6.1%, unadjusted OR: 0.49, 95% CI: 0.34-0.71, P < 0.01) and non-ST-segment elevation myocardial infarction subpopulation (1.5% versus 2.9%, unadjusted OR: 0.51, 95% CI: 0.33-0.79, P < 0.01). However, in unstable angina subpopulation, the in-hospital cardiac death rate was comparable between both groups. In conclusion, the use of pm-procedural beta-blocker was associated with a lower risk of in-hospital cardiac death in patients with ACS undergoing PCI. This result adds to the body of evidence that use of pre-procedural beta-blocker in patients with ACS might be reasonable. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | INT HEART JOURNAL ASSOC | - |
dc.subject | ACUTE MYOCARDIAL-INFARCTION | - |
dc.subject | ASSOCIATION TASK-FORCE | - |
dc.subject | AMERICAN-COLLEGE | - |
dc.subject | HEART-FAILURE | - |
dc.subject | MANAGEMENT | - |
dc.subject | MORTALITY | - |
dc.subject | THERAPY | - |
dc.subject | METOPROLOL | - |
dc.subject | GUIDELINE | - |
dc.subject | PROPRANOLOL | - |
dc.title | Effect of Pre-Procedural Beta-Blocker on Clinical Outcome after Percutaneous Coronary Intervention in Acute Coronary Syndrome From the 2014 K-PCI Registry | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Rha, Seung-Woon | - |
dc.identifier.doi | 10.1536/ihj.19-175 | - |
dc.identifier.scopusid | 2-s2.0-85075735862 | - |
dc.identifier.wosid | 000499995000009 | - |
dc.identifier.bibliographicCitation | INTERNATIONAL HEART JOURNAL, v.60, no.6, pp.1284 - 1292 | - |
dc.relation.isPartOf | INTERNATIONAL HEART JOURNAL | - |
dc.citation.title | INTERNATIONAL HEART JOURNAL | - |
dc.citation.volume | 60 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 1284 | - |
dc.citation.endPage | 1292 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Cardiovascular System & Cardiology | - |
dc.relation.journalWebOfScienceCategory | Cardiac & Cardiovascular Systems | - |
dc.subject.keywordPlus | ACUTE MYOCARDIAL-INFARCTION | - |
dc.subject.keywordPlus | ASSOCIATION TASK-FORCE | - |
dc.subject.keywordPlus | AMERICAN-COLLEGE | - |
dc.subject.keywordPlus | HEART-FAILURE | - |
dc.subject.keywordPlus | MANAGEMENT | - |
dc.subject.keywordPlus | MORTALITY | - |
dc.subject.keywordPlus | THERAPY | - |
dc.subject.keywordPlus | METOPROLOL | - |
dc.subject.keywordPlus | GUIDELINE | - |
dc.subject.keywordPlus | PROPRANOLOL | - |
dc.subject.keywordAuthor | Coronary artery disease | - |
dc.subject.keywordAuthor | Pre-procedural medication | - |
dc.subject.keywordAuthor | Cardiac death | - |
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