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Incidence and Risk Factors for Venous Thromboembolism After Spine Surgery in Korean Patients

Authors
Park, Ji HyunLee, Kyung EunYu, Yun MiPark, Youngja HwangChoi, Soo An
Issue Date
8월-2019
Publisher
ELSEVIER SCIENCE INC
Keywords
HIRA-NIS-2014; Incidence; Risk factors; Spine surgery; Venous thromboembolism
Citation
WORLD NEUROSURGERY, v.128, pp.E289 - E307
Indexed
SCIE
SCOPUS
Journal Title
WORLD NEUROSURGERY
Volume
128
Start Page
E289
End Page
E307
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/63622
DOI
10.1016/j.wneu.2019.04.140
ISSN
1878-8750
Abstract
BACKGROUND: Data regarding the incidence of venous thromboembolism (VTE) after spine surgery are scarce. Identifying ideal candidates for pharmacologic thromboprophylaxis and balancing the risk of thromboembolic complications against the risk of permanent neurologic deficits from a spinal epidural hematoma (SEH) are difficult. Even guidelines cannot suggest the standard of thromboprophylaxis. OBJECTIVES: This study aimed to identify the incidence of and risk factors for VTE after spine surgery in the Korean population. In addition, the rate of pharmacoprophylaxis and the incidence of SEH after spine surgery were analyzed. METHODS: The study cohort was generated by extracting patients with disease codes of spine surgery and VTE from the Health Insurance Review & Assessment Service National Inpatient Sample in 2014. After analyzing the incidence of VTE after spine surgery, a univariate comparison was performed to examine the possible relationship between the incidence of VTE and the independent variable. Variables found to be significant were included in a multivariable analysis model for further analysis. RESULTS: The incidence of VTE was 2.09% among all 21,261 patients who had spine surgery, and prophylaxis was applied to 7.89% of all patients who had spine surgery. Comorbidities and surgery-related risk factors were venous disease, cancer, respiratory disease, prolonged surgery hours, and increased total blood loss. Hospital-related risk factors were the location and hospital size. CONCLUSIONS: On the basis of the incidence of VTE and the risk factors, more active prophylaxis is suggested for patients in the Korean population who undergo spine surgery.
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