Multicenter Prospective Study of Laparoscopic Nissen Fundoplication for Gastroesophageal Reflux Disease in Korea
DC Field | Value | Language |
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dc.contributor.author | Park, Sungsoo | - |
dc.contributor.author | Park, Joong-Min | - |
dc.contributor.author | Kim, Jin-Jo | - |
dc.contributor.author | Lee, In-Seob | - |
dc.contributor.author | Han, Sang-Uk | - |
dc.contributor.author | Seo, Kyung Won | - |
dc.contributor.author | Kwon, Jin Won | - |
dc.date.accessioned | 2021-09-01T13:23:48Z | - |
dc.date.available | 2021-09-01T13:23:48Z | - |
dc.date.created | 2021-06-19 | - |
dc.date.issued | 2019-07 | - |
dc.identifier.issn | 2093-0879 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/64607 | - |
dc.description.abstract | Backgrounds/Aims This multicenter study aims to evaluate the effect and feasibility of anti-reflux surgery compared with medical treatment for gastroesophageal reflux disease (GERD). Methods Patients with GERD who were undergoing medical treatment with proton pump inhibitors for more than 8 weeks and those who were scheduled to undergo anti-reflux surgery were enrolled. Efficacy of pre-operative medical treatment was evaluated retrospectively and effect of anti-reflux surgery was prospectively evaluated at 1 week and 3 months after surgery. Quality of life (QOL) was also investigated before and after surgery. Results Between February and October 2018, 51 patients underwent laparoscopic Nissen fundoplication for treating GERD at 5 hospitals in Korea. Thirty-four patients (66.7%) showed poor proton pump inhibitor response. At 3 months after surgery, heartburn was completely resolved in 87.9% patients and partially improved in 9.1%. Acid regurgitation was completely resolved in 82.9% and partially improved in 11.4%. Atypical extraesophageal symptoms were completely controlled in 45.5% and partially controlled in 36.4%. GERD-related QOL scores at 1 week after surgery significantly improved compared with pre-operative scores. There was no difference in GERD-related QOL scores between 1 week and 3 months after surgery. General QOL measured with European QOL-5 dimensions and health-related QOL instrument with 8 items significantly improved after anti-reflux surgery. Satisfaction with treatment was significantly higher after surgery than before surgery (72.5% vs 11.8%, P < 0.001). Conclusion Anti-reflux surgery improved GERD symptoms and QOL in patients. Anti-reflux surgery is an effective treatment option compared with medical treatment for GERD patients selected for surgical treatment. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | KOREAN SOC NEUROGASTROENTEROLOGY & MOTILITY | - |
dc.subject | QUALITY-OF-LIFE | - |
dc.subject | ANTIREFLUX SURGERY | - |
dc.subject | OUTCOMES | - |
dc.subject | TERM | - |
dc.subject | SYMPTOMS | - |
dc.subject | GERD | - |
dc.title | Multicenter Prospective Study of Laparoscopic Nissen Fundoplication for Gastroesophageal Reflux Disease in Korea | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Park, Sungsoo | - |
dc.identifier.doi | 10.5056/jnm19059 | - |
dc.identifier.scopusid | 2-s2.0-85073906491 | - |
dc.identifier.wosid | 000476655500007 | - |
dc.identifier.bibliographicCitation | JOURNAL OF NEUROGASTROENTEROLOGY AND MOTILITY, v.25, no.3, pp.394 - 402 | - |
dc.relation.isPartOf | JOURNAL OF NEUROGASTROENTEROLOGY AND MOTILITY | - |
dc.citation.title | JOURNAL OF NEUROGASTROENTEROLOGY AND MOTILITY | - |
dc.citation.volume | 25 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 394 | - |
dc.citation.endPage | 402 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART002491269 | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Gastroenterology & Hepatology | - |
dc.relation.journalResearchArea | Neurosciences & Neurology | - |
dc.relation.journalWebOfScienceCategory | Gastroenterology & Hepatology | - |
dc.relation.journalWebOfScienceCategory | Clinical Neurology | - |
dc.subject.keywordPlus | QUALITY-OF-LIFE | - |
dc.subject.keywordPlus | ANTIREFLUX SURGERY | - |
dc.subject.keywordPlus | OUTCOMES | - |
dc.subject.keywordPlus | TERM | - |
dc.subject.keywordPlus | SYMPTOMS | - |
dc.subject.keywordPlus | GERD | - |
dc.subject.keywordAuthor | Fundoplication | - |
dc.subject.keywordAuthor | Gastroesophageal reflux | - |
dc.subject.keywordAuthor | Laparoscopy | - |
dc.subject.keywordAuthor | Quality of life | - |
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