Electrical Impedance as a Biomarker for Inner Ear Pathology Following Lateral Wall and Peri-modiolar Cochlear Implantation
DC Field | Value | Language |
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dc.contributor.author | Shaul, Chanan | - |
dc.contributor.author | Bester, Christofer W. | - |
dc.contributor.author | Weder, Stefan | - |
dc.contributor.author | Choi, June | - |
dc.contributor.author | Eastwood, Hayden | - |
dc.contributor.author | Padmavathi, K., V | - |
dc.contributor.author | Collins, Aaron | - |
dc.contributor.author | O'Leary, Stephen J. | - |
dc.date.accessioned | 2021-09-01T14:32:50Z | - |
dc.date.available | 2021-09-01T14:32:50Z | - |
dc.date.created | 2021-06-19 | - |
dc.date.issued | 2019-06 | - |
dc.identifier.issn | 1531-7129 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/65230 | - |
dc.description.abstract | Objectives/Hypothesis: Spikes in cochlear implant impedance are associated with inner ear pathology after implantation. Here, we correlate these spikes with episodes of hearing loss and/or vertigo, with a comparison between lateral wall and peri-modiolar electrode arrays. Methods: Seven hundred seventy recipients of Cochlear's slim-straight, lateral wall electrode (CI422), or peri-modiolar (CI512) electrode were investigated for impedance spikes. Impedance fluctuations were defined as a median rise of > 4 k Omega across all intracochlear electrodes from baseline measurements taken 2 weeks after switch-on. Medical records were analyzed from 189 of the 770 patients. Results: The slim straight, lateral wall electrode was found to spike in impedance at a significantly higher rate than the peri-modiolar array (17% vs 12%). The peri-modiolar electrode tended to spike in impedance earlier than the slim-straight electrode. Impedance spikes were found to significantly correlate with medical events (hearing loss, vertigo, or tinnitus). Overall, in the "spike" group, 42 of 75 patients (56%) demonstrated a clinical event during the impedance spike, whereas 26 of 114 patients (22%) of the "non-spike" group had a clinical event. This significant difference existed with both implant types. Conclusion: These results demonstrate a small, but significant increase in impedance spikes in lateral wall electrodes, and support the relationship between spikes in cochlear implant impedances and postoperative inner-ear events, including the loss of residual hearing and vertigo. Monitoring cochlear implant impedance may be a method for early detection, and so the prevention, of these events in the future. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | LIPPINCOTT WILLIAMS & WILKINS | - |
dc.subject | MODIFIED ELECTRODE SURFACES | - |
dc.subject | ENDOLYMPHATIC HYDROPS | - |
dc.subject | POSTOPERATIVE IMPEDANCES | - |
dc.subject | INFLAMMATION | - |
dc.subject | HISTOPATHOLOGY | - |
dc.subject | LEVEL | - |
dc.title | Electrical Impedance as a Biomarker for Inner Ear Pathology Following Lateral Wall and Peri-modiolar Cochlear Implantation | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Choi, June | - |
dc.identifier.doi | 10.1097/MAO.0000000000002227 | - |
dc.identifier.scopusid | 2-s2.0-85066061718 | - |
dc.identifier.wosid | 000480679800006 | - |
dc.identifier.bibliographicCitation | OTOLOGY & NEUROTOLOGY, v.40, no.5, pp.E518 - E526 | - |
dc.relation.isPartOf | OTOLOGY & NEUROTOLOGY | - |
dc.citation.title | OTOLOGY & NEUROTOLOGY | - |
dc.citation.volume | 40 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | E518 | - |
dc.citation.endPage | E526 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Neurosciences & Neurology | - |
dc.relation.journalResearchArea | Otorhinolaryngology | - |
dc.relation.journalWebOfScienceCategory | Clinical Neurology | - |
dc.relation.journalWebOfScienceCategory | Otorhinolaryngology | - |
dc.subject.keywordPlus | MODIFIED ELECTRODE SURFACES | - |
dc.subject.keywordPlus | ENDOLYMPHATIC HYDROPS | - |
dc.subject.keywordPlus | POSTOPERATIVE IMPEDANCES | - |
dc.subject.keywordPlus | INFLAMMATION | - |
dc.subject.keywordPlus | HISTOPATHOLOGY | - |
dc.subject.keywordPlus | LEVEL | - |
dc.subject.keywordAuthor | Biomarkers | - |
dc.subject.keywordAuthor | Cochlear implant | - |
dc.subject.keywordAuthor | Hearing loss | - |
dc.subject.keywordAuthor | Impedance | - |
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