Clinical Value of Whole Blood Procalcitonin Using Point of Care Testing, Quick Sequential Organ Failure Assessment Score, C-Reactive Protein and Lactate in Emergency Department Patients with Suspected Infection
DC Field | Value | Language |
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dc.contributor.author | Shim, Bo-Sun | - |
dc.contributor.author | Yoon, Young-Hoon | - |
dc.contributor.author | Kim, Jung-Youn | - |
dc.contributor.author | Cho, Young-Duck | - |
dc.contributor.author | Park, Sung-Jun | - |
dc.contributor.author | Lee, Eu-Sun | - |
dc.contributor.author | Choi, Sung-Hyuk | - |
dc.date.accessioned | 2021-09-01T14:35:46Z | - |
dc.date.available | 2021-09-01T14:35:46Z | - |
dc.date.created | 2021-06-19 | - |
dc.date.issued | 2019-06 | - |
dc.identifier.issn | 2077-0383 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/65257 | - |
dc.description.abstract | We investigated the clinical value of whole blood procalcitonin using point of care testing, quick sequential organ failure assessment score, C-reactive protein and lactate in emergency department patients with suspected infection and assessed the accuracy of the whole blood procalcitonin test by point-of-care testing. Participants were randomly selected from emergency department patients who complained of a febrile sense, had suspected infection and underwent serum procalcitonin testing. Whole blood procalcitonin levels by point-of-care testing were compared with serum procalcitonin test results from the laboratory. Participants were divided into two groups-those with bacteremia and those without bacteremia. Sensitivity, specificity, positive predictive value, negative predictive value of procalcitonin, lactate and Quick Sepsis-related Organ Failure Assessment scores were investigated in each group. Area under receiving operating curve of C-reactive protein, lactate and procalcitonin for predicting bacteremia and 28-day mortality were also evaluated. Whole blood procalcitonin had an excellent correlation with serum procalcitonin. The negative predictive value of procalcitonin and lactate was over 90%. Area under receiving operating curve results proved whole blood procalcitonin to be fair in predicting bacteremia or 28-day mortality. In the emergency department, point-of-care testing of whole blood procalcitonin is as accurate as laboratory testing. Moreover, procalcitonin is a complementing test together with lactate for predicting 28-days mortality and bacteremia for patients with suspected infection. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | MDPI | - |
dc.subject | SERUM LACTATE | - |
dc.subject | SEVERE SEPSIS | - |
dc.subject | MORTALITY | - |
dc.subject | LENGTH | - |
dc.subject | DEFINITIONS | - |
dc.subject | ACCURACY | - |
dc.subject | CRITERIA | - |
dc.subject | MARKERS | - |
dc.subject | IMPACT | - |
dc.title | Clinical Value of Whole Blood Procalcitonin Using Point of Care Testing, Quick Sequential Organ Failure Assessment Score, C-Reactive Protein and Lactate in Emergency Department Patients with Suspected Infection | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Yoon, Young-Hoon | - |
dc.contributor.affiliatedAuthor | Kim, Jung-Youn | - |
dc.contributor.affiliatedAuthor | Choi, Sung-Hyuk | - |
dc.identifier.doi | 10.3390/jcm8060833 | - |
dc.identifier.wosid | 000475349300077 | - |
dc.identifier.bibliographicCitation | JOURNAL OF CLINICAL MEDICINE, v.8, no.6 | - |
dc.relation.isPartOf | JOURNAL OF CLINICAL MEDICINE | - |
dc.citation.title | JOURNAL OF CLINICAL MEDICINE | - |
dc.citation.volume | 8 | - |
dc.citation.number | 6 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | General & Internal Medicine | - |
dc.relation.journalWebOfScienceCategory | Medicine, General & Internal | - |
dc.subject.keywordPlus | SERUM LACTATE | - |
dc.subject.keywordPlus | SEVERE SEPSIS | - |
dc.subject.keywordPlus | MORTALITY | - |
dc.subject.keywordPlus | LENGTH | - |
dc.subject.keywordPlus | DEFINITIONS | - |
dc.subject.keywordPlus | ACCURACY | - |
dc.subject.keywordPlus | CRITERIA | - |
dc.subject.keywordPlus | MARKERS | - |
dc.subject.keywordPlus | IMPACT | - |
dc.subject.keywordAuthor | procalcitonin | - |
dc.subject.keywordAuthor | point-of-care testing | - |
dc.subject.keywordAuthor | bacteremia | - |
dc.subject.keywordAuthor | mortality | - |
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