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Examining Patterns of Polypharmacy in Bipolar Disorder: Findings from the REAP-BD, Korea

Authors
Kim, KiwonYang, HyunjuNa, EuihyeonLee, HoseonJang, Ok-JinYoon, Hyung-JunOh, Hong SeokHam, Byung-JooPark, Seon-CheolLin, Shih-KuTan, Chay HoonShinfuku, NaotakaPark, Yong Chon
Issue Date
5월-2019
Publisher
KOREAN NEUROPSYCHIATRIC ASSOC
Keywords
Polypharmacy; Bipolar disorder; Inpatient; Antidepressant
Citation
PSYCHIATRY INVESTIGATION, v.16, no.5, pp.397 - 402
Indexed
SCIE
SSCI
SCOPUS
KCI
Journal Title
PSYCHIATRY INVESTIGATION
Volume
16
Number
5
Start Page
397
End Page
402
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/65905
DOI
10.30773/pi.2019.02.26.4
ISSN
1738-3684
Abstract
Based on Korean data from the Research on Asian Psychotropic Prescription Pattern for Bipolar Disorder, this study tried to present prescription patterns in biopolar disorder (BD) and its associated clinical features. Based on the information obtained from the study with structured questions, the tendency of prescription pattern was studied and analyzed. Polypharmacy was predominant, including simple polypharmacy in 51.1% and complex polypharmacy in 34.2% of patients. Subjects associated with simple or complex polypharmacy were significantly younger, had higher inpatient settings, a larger portion of onset with manic episode, a shorter duration of untreated illness, a shorter duration of current episode, were more overweight, used less antidepressants and used more anxiolytics. These findings can suggest higher polypharmacy rate in more severe BD and highlight the necessity of monitoring the weight of subjects with polypharmacy.
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