Assessment of patient-reported outcomes (PROs): treatment satisfaction, medication adherence, and quality of life (QoL) and the associated factors in postmenopausal osteoporosis (PMO) patients in Korea
DC Field | Value | Language |
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dc.contributor.author | Byun, Dong Won | - |
dc.contributor.author | Moon, Seong-Hwan | - |
dc.contributor.author | Kim, Tak | - |
dc.contributor.author | Lee, Hae-Hyeog | - |
dc.contributor.author | Park, Hyoung Moo | - |
dc.contributor.author | Kang, Moo-Il | - |
dc.contributor.author | Ha, Yong-Chan | - |
dc.contributor.author | Chung, Ho-Yeon | - |
dc.contributor.author | Yoon, Byung-Koo | - |
dc.contributor.author | Kim, Tae-Young | - |
dc.contributor.author | Chae, Soo Uk | - |
dc.contributor.author | Shin, Chan Soo | - |
dc.contributor.author | Yang, Kyu-Hyun | - |
dc.contributor.author | Lee, Jae Hyup | - |
dc.contributor.author | Chang, Jae Suk | - |
dc.contributor.author | Kim, Sung Hoon | - |
dc.contributor.author | Kim, In Joo | - |
dc.contributor.author | Koh, Jung-Min | - |
dc.contributor.author | Jung, Jung Hwa | - |
dc.contributor.author | Yi, Kyong Wook | - |
dc.contributor.author | Yoo, Jeong Joon | - |
dc.contributor.author | Chung, Dong Jin | - |
dc.contributor.author | Lee, Young-Kyun | - |
dc.contributor.author | Yoon, Hyun-Koo | - |
dc.contributor.author | Hong, Seongbin | - |
dc.contributor.author | Kim, Deog-Yoon | - |
dc.contributor.author | Baek, Ki Hyun | - |
dc.contributor.author | Kim, Hyun-Joo | - |
dc.contributor.author | Kim, Young-Joo | - |
dc.contributor.author | Kang, Seongsik | - |
dc.contributor.author | Min, Yong-Ki | - |
dc.date.accessioned | 2021-09-01T15:56:36Z | - |
dc.date.available | 2021-09-01T15:56:36Z | - |
dc.date.created | 2021-06-18 | - |
dc.date.issued | 2019-05 | - |
dc.identifier.issn | 0914-8779 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/65945 | - |
dc.description.abstract | Patient-reported outcomes (PROs) provide practical guides for treatment; however, studies that have evaluated PROs of women in Korea with postmenopausal osteoporosis (PMO) are lacking. This cross-sectional, multi-center (29 nationwide hospitals) study, performed from March 2013 to July 2014, aimed to assess PROs related to treatment satisfaction, medication adherence, and quality of life (QoL) in Korean PMO women using osteoporosis medication for prevention/treatment. Patient demographics, clinical characteristics, treatment patterns, PROs, and experience using medication were collected. The 14-item Treatment Satisfaction Questionnaire for Medication (TSQM) (score-range, 0-100; domains: effectiveness, side effects, convenience, global satisfaction), Osteoporosis-Specific Morisky Medication Adherence Scale (OS-MMAS) (score-range, 0-8), and EuroQol-5 dimensions questionnaire (index score range, -0.22 to 1.0; EuroQol visual analog scale score range, 0-100) were used. To investigate factors associated with PROs, linear (treatment satisfaction/QoL) or logistic (medication adherence) regression analyses were conducted. A total of 1804 patients (age, 62years) were investigated; 60.1% used bisphosphonate, with the majority (67.2%) using weekly medication, 27.8% used daily hormone replacement therapy, and 12.1% used daily selective estrogen receptor modulator. Several patients reported gastrointestinal (GI) events (31.6%) and dental visits due to problems (24.1%) while using medication. Factors associated with the highest OS-MMAS domain scores were convenience and global satisfaction. GI events were associated with non-adherence. TSQM scores for effectiveness, side effects, and GI risk factors were significantly associated with QoL. Our study elaborately assessed the factors associated with PROs of Korean PMO women. Based on our findings, appropriate treatment-related adjustments such as frequency/choice of medications and GI risk management may improve PROs. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | SPRINGER JAPAN KK | - |
dc.subject | CLINICAL-PRACTICE | - |
dc.subject | HEALTH-STATUS | - |
dc.subject | FRACTURE | - |
dc.subject | THERAPY | - |
dc.subject | WOMEN | - |
dc.subject | ALENDRONATE | - |
dc.subject | PREVALENCE | - |
dc.subject | PREVENTION | - |
dc.subject | RALOXIFENE | - |
dc.subject | HISTORY | - |
dc.title | Assessment of patient-reported outcomes (PROs): treatment satisfaction, medication adherence, and quality of life (QoL) and the associated factors in postmenopausal osteoporosis (PMO) patients in Korea | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Tak | - |
dc.contributor.affiliatedAuthor | Yi, Kyong Wook | - |
dc.identifier.doi | 10.1007/s00774-018-0956-6 | - |
dc.identifier.scopusid | 2-s2.0-85053797997 | - |
dc.identifier.wosid | 000466447800019 | - |
dc.identifier.bibliographicCitation | JOURNAL OF BONE AND MINERAL METABOLISM, v.37, no.3, pp.563 - 572 | - |
dc.relation.isPartOf | JOURNAL OF BONE AND MINERAL METABOLISM | - |
dc.citation.title | JOURNAL OF BONE AND MINERAL METABOLISM | - |
dc.citation.volume | 37 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 563 | - |
dc.citation.endPage | 572 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Endocrinology & Metabolism | - |
dc.relation.journalResearchArea | Research & Experimental Medicine | - |
dc.relation.journalWebOfScienceCategory | Endocrinology & Metabolism | - |
dc.relation.journalWebOfScienceCategory | Medicine, Research & Experimental | - |
dc.subject.keywordPlus | CLINICAL-PRACTICE | - |
dc.subject.keywordPlus | HEALTH-STATUS | - |
dc.subject.keywordPlus | FRACTURE | - |
dc.subject.keywordPlus | THERAPY | - |
dc.subject.keywordPlus | WOMEN | - |
dc.subject.keywordPlus | ALENDRONATE | - |
dc.subject.keywordPlus | PREVALENCE | - |
dc.subject.keywordPlus | PREVENTION | - |
dc.subject.keywordPlus | RALOXIFENE | - |
dc.subject.keywordPlus | HISTORY | - |
dc.subject.keywordAuthor | Postmenopausal osteoporosis | - |
dc.subject.keywordAuthor | Treatment satisfaction | - |
dc.subject.keywordAuthor | Medication adherence | - |
dc.subject.keywordAuthor | Quality of life | - |
dc.subject.keywordAuthor | Gastrointestinal events | - |
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