Dual-energy CT iodine quantification for characterizing focal thyroid lesions
- Authors
- Lee, Do Hyung; Lee, Young Hen; Seo, Hyung Suk; Lee, Ki Yeol; Suh, Sang-il; Ryoo, Inseon; You, Sung-Hye; Kim, Byungjun; Yang, Kyung-Sook
- Issue Date
- 4월-2019
- Publisher
- WILEY
- Keywords
- CT; diagnosis; differential; dual-energy; iodin; analysis; thyroid nodule
- Citation
- HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, v.41, no.4, pp.1024 - 1031
- Indexed
- SCIE
SCOPUS
- Journal Title
- HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
- Volume
- 41
- Number
- 4
- Start Page
- 1024
- End Page
- 1031
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/66436
- DOI
- 10.1002/hed.25524
- ISSN
- 1043-3074
- Abstract
- Background To determine the usefulness of dual-energy CT (DECT) iodine quantification to classify the focal thyroid lesions. Methods We retrospectively enrolled a total of 76 cytopathologically confirmed focal thyroid lesions (mean size: 1.9 cm). After drawing a region of interest on the DECT-derived iodine maps, the obtained iodine concentration values of thyroid nodules (IC_N) and normalized IC_N were compared between 3 groups: papillary thyroid carcinoma (PTC), benign nodule, and cyst. Results From all lesions, 46, 17, and 13 were assigned to the PTC, benign nodule, and cyst groups. IC_N was the highest in the benign nodule, lower in the PTC, and the lowest in the cyst (median [interquartile range]: 4.3 [3.13-5.48], 3.15 [2.29-4.01], 0.60 [0.33-0.88], all P < .001). Similarly, the normalized IC_N values were all statistically different from each other (P < .05).The multi-class area under the curves using the optimal cutoff values were 0.931 for IC_N and 0.918, 0.920 for normalized IC, respectively. Conclusion DECT iodine quantification could be helpful to classify the focal thyroid lesions.
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Collections - College of Medicine > Department of Medical Science > 1. Journal Articles
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