Evolutionary relationship analysis of Middle East respiratory syndrome coronavirus 4a and 4b protein coding sequences
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Jin Il | - |
dc.contributor.author | Park, Sehee | - |
dc.contributor.author | Bae, Joon-Yong | - |
dc.contributor.author | Park, Man-Seong | - |
dc.date.accessioned | 2021-09-01T18:06:37Z | - |
dc.date.available | 2021-09-01T18:06:37Z | - |
dc.date.created | 2021-06-19 | - |
dc.date.issued | 2019-03 | - |
dc.identifier.issn | 1229-845X | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/67130 | - |
dc.description.abstract | The 4a and 4b proteins of the Middle East respiratory syndrome coronavirus (MERS-CoV) have been described for their antagonism on host innate immunity. However, unlike clustering patterns of the complete gene sequences of human and camel MERS-CoVs, the 4a and 4b protein coding regions did not constitute species-specific phylogenetic groups. Moreover, given the estimated evolutionary rates of the complete, 4a, and 4b gene sequences, the 4a and 4b proteins might be less affected by species-specific innate immune pressures. These results suggest that the 4a and 4b proteins of MERS-CoV may function against host innate immunity in a manner independent of host species and/or evolutionary clustering patterns. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | KOREAN SOC VETERINARY SCIENCE | - |
dc.title | Evolutionary relationship analysis of Middle East respiratory syndrome coronavirus 4a and 4b protein coding sequences | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Jin Il | - |
dc.contributor.affiliatedAuthor | Park, Man-Seong | - |
dc.identifier.doi | 10.4142/jvs.2019.20.e1 | - |
dc.identifier.scopusid | 2-s2.0-85064239293 | - |
dc.identifier.wosid | 000469249400001 | - |
dc.identifier.bibliographicCitation | JOURNAL OF VETERINARY SCIENCE, v.20, no.2 | - |
dc.relation.isPartOf | JOURNAL OF VETERINARY SCIENCE | - |
dc.citation.title | JOURNAL OF VETERINARY SCIENCE | - |
dc.citation.volume | 20 | - |
dc.citation.number | 2 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART002451340 | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Veterinary Sciences | - |
dc.relation.journalWebOfScienceCategory | Veterinary Sciences | - |
dc.subject.keywordAuthor | Middle East respiratory syndrome coronavirus | - |
dc.subject.keywordAuthor | molecular evolution | - |
dc.subject.keywordAuthor | phylogeny | - |
dc.subject.keywordAuthor | zoonoses | - |
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