A protecting group-free divergent synthesis of natural benzofurans via one-pot synthesis of 2-bromo-6-hydroxybenzofurans
- Authors
- Sivaraman, Aneesh; Harmalkar, Dipesh S.; Kang, Jiyoon; Choi, Yongseok; Lee, Kyeong
- Issue Date
- 28-2월-2019
- Publisher
- ROYAL SOC CHEMISTRY
- Citation
- ORGANIC & BIOMOLECULAR CHEMISTRY, v.17, no.8, pp.2153 - 2161
- Indexed
- SCIE
SCOPUS
- Journal Title
- ORGANIC & BIOMOLECULAR CHEMISTRY
- Volume
- 17
- Number
- 8
- Start Page
- 2153
- End Page
- 2161
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/67266
- DOI
- 10.1039/c8ob03102a
- ISSN
- 1477-0520
- Abstract
- 2-Bromo-6-hydroxybenzofurans are potentially versatile intermediates for the divergent synthesis of numerous benzofuran-based natural products and their analogues. Herein we report the first one-pot strategy for the efficient synthesis of 2-bromo-6-hydroxybenzofurans. The present protocol provides shorter routes for the synthesis of moracins M, N, O and P; gramniphenols F and G; and morunigrol C using a protecting group-free approach.
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Collections - Graduate School > Department of Biotechnology > 1. Journal Articles
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