Definition of treatment-resistant depression - Asia Pacific perspectives
DC Field | Value | Language |
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dc.contributor.author | Ng, C. H. | - |
dc.contributor.author | Kato, T. | - |
dc.contributor.author | Han, C. | - |
dc.contributor.author | Wang, G. | - |
dc.contributor.author | Trivedi, M. | - |
dc.contributor.author | Ramesh, V. | - |
dc.contributor.author | Shao, D. | - |
dc.contributor.author | Gala, S. | - |
dc.contributor.author | Narayanan, S. | - |
dc.contributor.author | Tan, W. | - |
dc.contributor.author | Feng, Y. | - |
dc.contributor.author | Kasper, S. | - |
dc.date.accessioned | 2021-09-01T19:04:23Z | - |
dc.date.available | 2021-09-01T19:04:23Z | - |
dc.date.created | 2021-06-19 | - |
dc.date.issued | 2019-02-15 | - |
dc.identifier.issn | 0165-0327 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/67629 | - |
dc.description.abstract | Background: The lack of uniformity in the definition of treatment resistant depression (TRD) within the Asia-Pacific (APAC) region may have implications for patient management. We aimed to characterize the most commonly used TRD definition in selected APAC countries. Methods: A systematic literature review of TRD definitions in APAC countries was conducted in Medline and Embase (2010-2016) and conference proceedings (2014 and 2016). TRD guidelines (APAC, Europe regional, US, or international) were also searched. An expert-panel explored APAC nuances in TRD definitions to achieve consensus for a regional-level definition. Results: Ten guidelines and 89 studies qualified for study inclusion. Among the studies, variations were observed in definitions regarding: number of antidepressants failed (range: (3) 1 to (3) 3), classes of antidepressants (same or different; 59% did not specify class), duration of previous treatments (range: 4-12 weeks), dosage adequacy, and consideration of adherence (yes/no; 88% of studies did not consider adherence). No TRD-specific guidelines were identified. The emerging consensus from the literature review and panel discussion was that TRD is most commonly defined as failure to (3) 2 antidepressant therapies given at adequate doses, for 6-8 weeks during a major depressive episode. Limitations: Few studies provided definitions of TRD used in daily clinical practice, and a limited number of countries were represented in the included studies and expert panel. Conclusion: Attaining consensus on TRD definition may promote accurate, and possibly early detection of patients with TRD to enable appropriate intervention that may impact patient outcomes and quality of life. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCIENCE BV | - |
dc.subject | TRANSCRANIAL MAGNETIC STIMULATION | - |
dc.subject | THETA-BURST STIMULATION | - |
dc.subject | ELECTROCONVULSIVE-THERAPY | - |
dc.subject | RANDOMIZED-TRIAL | - |
dc.subject | DOUBLE-BLIND | - |
dc.subject | OPEN-LABEL | - |
dc.subject | FOLLOW-UP | - |
dc.subject | ARIPIPRAZOLE AUGMENTATION | - |
dc.subject | ANTIDEPRESSANT TREATMENT | - |
dc.subject | FUNCTIONAL CONNECTIVITY | - |
dc.title | Definition of treatment-resistant depression - Asia Pacific perspectives | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Han, C. | - |
dc.identifier.doi | 10.1016/j.jad.2018.11.038 | - |
dc.identifier.scopusid | 2-s2.0-85056454693 | - |
dc.identifier.wosid | 000456697100078 | - |
dc.identifier.bibliographicCitation | JOURNAL OF AFFECTIVE DISORDERS, v.245, pp.626 - 636 | - |
dc.relation.isPartOf | JOURNAL OF AFFECTIVE DISORDERS | - |
dc.citation.title | JOURNAL OF AFFECTIVE DISORDERS | - |
dc.citation.volume | 245 | - |
dc.citation.startPage | 626 | - |
dc.citation.endPage | 636 | - |
dc.type.rims | ART | - |
dc.type.docType | Review | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | ssci | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Neurosciences & Neurology | - |
dc.relation.journalResearchArea | Psychiatry | - |
dc.relation.journalWebOfScienceCategory | Clinical Neurology | - |
dc.relation.journalWebOfScienceCategory | Psychiatry | - |
dc.subject.keywordPlus | TRANSCRANIAL MAGNETIC STIMULATION | - |
dc.subject.keywordPlus | THETA-BURST STIMULATION | - |
dc.subject.keywordPlus | ELECTROCONVULSIVE-THERAPY | - |
dc.subject.keywordPlus | RANDOMIZED-TRIAL | - |
dc.subject.keywordPlus | DOUBLE-BLIND | - |
dc.subject.keywordPlus | OPEN-LABEL | - |
dc.subject.keywordPlus | FOLLOW-UP | - |
dc.subject.keywordPlus | ARIPIPRAZOLE AUGMENTATION | - |
dc.subject.keywordPlus | ANTIDEPRESSANT TREATMENT | - |
dc.subject.keywordPlus | FUNCTIONAL CONNECTIVITY | - |
dc.subject.keywordAuthor | Treatment resistant depression | - |
dc.subject.keywordAuthor | Asia-pacific | - |
dc.subject.keywordAuthor | Definition | - |
dc.subject.keywordAuthor | Consensus | - |
dc.subject.keywordAuthor | Systematic literature review | - |
dc.subject.keywordAuthor | Expert panel | - |
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