Pluronics: Intelligent building units for targeted cancer therapy and molecular imaging
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Ul Khaliq, Nisar | - |
dc.contributor.author | Park, Dal Yong | - |
dc.contributor.author | Yun, Byeong Min | - |
dc.contributor.author | Yang, Da Hye | - |
dc.contributor.author | Jung, Yong Woo | - |
dc.contributor.author | Seo, Jae Hong | - |
dc.contributor.author | Hwang, Chang Soon | - |
dc.contributor.author | Yuk, Soon Hong | - |
dc.date.accessioned | 2021-09-01T19:06:21Z | - |
dc.date.available | 2021-09-01T19:06:21Z | - |
dc.date.created | 2021-06-19 | - |
dc.date.issued | 2019-02-10 | - |
dc.identifier.issn | 0378-5173 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/67645 | - |
dc.description.abstract | Pluronics are triblock copolymers, in which two hydrophilic poly (ethylene oxide) (PEO) blocks are connected via a hydrophobic poly propylene oxide (PPO) block. Because of their low molecular weight and high content of PEO, Pluronics have demonstrated the micellization phenomenon, which is dependent on temperature and/or concentration. With an understanding of micellization phenomenon in more detail, information on the morphology, micelle core radius, aggregation behavior with critical micelle concentration (CMC) and critical micelle temperature (CMT) and so on has been revealed. Based on this acquired information, various studies have been performed for biomedical applications such as drug delivery systems, tissue regeneration scaffolders, and biosurfactants. This review discusses the delivery of small molecules and macromolecules using Pluronic-based NPs and their composites. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCIENCE BV | - |
dc.subject | SOL-GEL TRANSITION | - |
dc.subject | OXIDE) TRIBLOCK COPOLYMERS | - |
dc.subject | BLOCK-COPOLYMERS | - |
dc.subject | DRUG-DELIVERY | - |
dc.subject | CORE/SHELL NANOPARTICLES | - |
dc.subject | MULTILAYER NANOPARTICLES | - |
dc.subject | MULTIDRUG-RESISTANCE | - |
dc.subject | IN-VITRO | - |
dc.subject | SUSTAINED DELIVERY | - |
dc.subject | POLYMER MICELLES | - |
dc.title | Pluronics: Intelligent building units for targeted cancer therapy and molecular imaging | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Jung, Yong Woo | - |
dc.contributor.affiliatedAuthor | Seo, Jae Hong | - |
dc.contributor.affiliatedAuthor | Yuk, Soon Hong | - |
dc.identifier.doi | 10.1016/j.ijpharm.2018.11.064 | - |
dc.identifier.scopusid | 2-s2.0-85058220167 | - |
dc.identifier.wosid | 000455968700004 | - |
dc.identifier.bibliographicCitation | INTERNATIONAL JOURNAL OF PHARMACEUTICS, v.556, pp.30 - 44 | - |
dc.relation.isPartOf | INTERNATIONAL JOURNAL OF PHARMACEUTICS | - |
dc.citation.title | INTERNATIONAL JOURNAL OF PHARMACEUTICS | - |
dc.citation.volume | 556 | - |
dc.citation.startPage | 30 | - |
dc.citation.endPage | 44 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
dc.relation.journalWebOfScienceCategory | Pharmacology & Pharmacy | - |
dc.subject.keywordPlus | SOL-GEL TRANSITION | - |
dc.subject.keywordPlus | OXIDE) TRIBLOCK COPOLYMERS | - |
dc.subject.keywordPlus | BLOCK-COPOLYMERS | - |
dc.subject.keywordPlus | DRUG-DELIVERY | - |
dc.subject.keywordPlus | CORE/SHELL NANOPARTICLES | - |
dc.subject.keywordPlus | MULTILAYER NANOPARTICLES | - |
dc.subject.keywordPlus | MULTIDRUG-RESISTANCE | - |
dc.subject.keywordPlus | IN-VITRO | - |
dc.subject.keywordPlus | SUSTAINED DELIVERY | - |
dc.subject.keywordPlus | POLYMER MICELLES | - |
dc.subject.keywordAuthor | Pluronic nanoparticles | - |
dc.subject.keywordAuthor | Phase transition | - |
dc.subject.keywordAuthor | Small molecules | - |
dc.subject.keywordAuthor | Macromolecules | - |
dc.subject.keywordAuthor | Doxorubicin | - |
dc.subject.keywordAuthor | In situ gel | - |
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