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Role of Inflammation in Psychiatric Disorders

Authors
Jeon, Sang WonYoon, Ho-KyoungKim, Yong-Ku
Issue Date
2019
Publisher
SPRINGER-VERLAG SINGAPORE PTE LTD
Keywords
Inflammation; Neuroinflammation; Cytokine; Psychiatric disorder; Depression; Medication
Citation
FRONTIERS IN PSYCHIATRY: ARTIFCIAL INTELLIGENCE, PRECISION MEDICINE, AND OTHER PARADIGM SHIFTS, v.1192, pp.491 - 501
Indexed
SCIE
SCOPUS
Journal Title
FRONTIERS IN PSYCHIATRY: ARTIFCIAL INTELLIGENCE, PRECISION MEDICINE, AND OTHER PARADIGM SHIFTS
Volume
1192
Start Page
491
End Page
501
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/68953
DOI
10.1007/978-981-32-9721-0_24
ISSN
0065-2598
Abstract
Psychiatric disorders are too multifactorial to be defined as a primarily-inflammatory disorder, and increased inflammatory response is not specific to mental disorder only. Numerous factors are involved in neuroinflammation, and there also are many confounding variables, making it difficult to obtain-consistent outcomes. Therefore, it is necessary to specify genetic, physiological, and epidemiological attributes of particular population groups vulnerable to inflammatory response as well as the disease subtypes. As of now, definitive inflammatory markers for psychiatric disorders have not been identified, but they could be very useful in patients with minimal vulnerability. In addition, it is possible to use inflammatory markers as depression biomarkers in subtypes of depression, which can serve as bases to develop medications to treat the disorder.
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