Fructose-1,6-bisphosphatase Inhibitors: A Review of Recent (2000-2017) Advances and Structure-Activity Relationship Studies
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Singh, Sarbjit | - |
dc.contributor.author | Harmalkar, Dipesh S. | - |
dc.contributor.author | Choi, Yongseok | - |
dc.contributor.author | Lee, Kyeong | - |
dc.date.accessioned | 2021-09-01T22:53:55Z | - |
dc.date.available | 2021-09-01T22:53:55Z | - |
dc.date.created | 2021-06-18 | - |
dc.date.issued | 2019 | - |
dc.identifier.issn | 0929-8673 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/69011 | - |
dc.description.abstract | Diabetes mellitus, commonly referred to as diabetes, is the 8th leading cause of death worldwide. As of 2015, approximately 415 million people were estimated to be diabetic worldwide, type 2 diabetes being the most common accounting for approximately 90-95% of all diagnosed cases with increasing prevalence. Fructose-1,6-bisphosphatase is one of the important therapeutic targets recently discovered to treat this chronic disease. In this focused review, we have highlighted recent advances and structure-activity relationship studies in the discovery and development of different fructose-1,6-bisphosphatase inhibitors reported since the year 2000. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | BENTHAM SCIENCE PUBL LTD | - |
dc.subject | FRUCTOSE 1,6-BISPHOSPHATASE | - |
dc.subject | ALLOSTERIC INHIBITORS | - |
dc.subject | BENZOXAZOLE BENZENESULFONAMIDES | - |
dc.subject | HEPATIC GLUCONEOGENESIS | - |
dc.subject | BIOLOGICAL EVALUATION | - |
dc.subject | DESIGN | - |
dc.subject | ACID | - |
dc.subject | DERIVATIVES | - |
dc.subject | DISCOVERY | - |
dc.subject | POTENT | - |
dc.title | Fructose-1,6-bisphosphatase Inhibitors: A Review of Recent (2000-2017) Advances and Structure-Activity Relationship Studies | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Choi, Yongseok | - |
dc.identifier.doi | 10.2174/0929867325666180831133734 | - |
dc.identifier.scopusid | 2-s2.0-85075086237 | - |
dc.identifier.wosid | 000493954800004 | - |
dc.identifier.bibliographicCitation | CURRENT MEDICINAL CHEMISTRY, v.26, no.29, pp.5542 - 5563 | - |
dc.relation.isPartOf | CURRENT MEDICINAL CHEMISTRY | - |
dc.citation.title | CURRENT MEDICINAL CHEMISTRY | - |
dc.citation.volume | 26 | - |
dc.citation.number | 29 | - |
dc.citation.startPage | 5542 | - |
dc.citation.endPage | 5563 | - |
dc.type.rims | ART | - |
dc.type.docType | Review | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Medicinal | - |
dc.relation.journalWebOfScienceCategory | Pharmacology & Pharmacy | - |
dc.subject.keywordPlus | FRUCTOSE 1,6-BISPHOSPHATASE | - |
dc.subject.keywordPlus | ALLOSTERIC INHIBITORS | - |
dc.subject.keywordPlus | BENZOXAZOLE BENZENESULFONAMIDES | - |
dc.subject.keywordPlus | HEPATIC GLUCONEOGENESIS | - |
dc.subject.keywordPlus | BIOLOGICAL EVALUATION | - |
dc.subject.keywordPlus | DESIGN | - |
dc.subject.keywordPlus | ACID | - |
dc.subject.keywordPlus | DERIVATIVES | - |
dc.subject.keywordPlus | DISCOVERY | - |
dc.subject.keywordPlus | POTENT | - |
dc.subject.keywordAuthor | Fructose-1,6-bisphosphatase inhibitors | - |
dc.subject.keywordAuthor | type 2 diabetes | - |
dc.subject.keywordAuthor | adenosine 5 &apos | - |
dc.subject.keywordAuthor | -monophosphate | - |
dc.subject.keywordAuthor | hyperglycemia | - |
dc.subject.keywordAuthor | diabetes mellitus | - |
dc.subject.keywordAuthor | chronic disease | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(02841) 서울특별시 성북구 안암로 14502-3290-1114
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.