Effectiveness of influenza and pneumococcal polysaccharide vaccines against influenza-related outcomes including pneumonia and acute exacerbation of cardiopulmonary diseases: Analysis by dominant viral subtype and vaccine matching
DC Field | Value | Language |
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dc.contributor.author | Song, Joon Young | - |
dc.contributor.author | Noh, Ji Yun | - |
dc.contributor.author | Lee, Jin Soo | - |
dc.contributor.author | Wie, Seong-Heon | - |
dc.contributor.author | Kim, Young Keun | - |
dc.contributor.author | Lee, Jacob | - |
dc.contributor.author | Jeong, Hye Won | - |
dc.contributor.author | Kim, Shin Woo | - |
dc.contributor.author | Lee, Sun Hee | - |
dc.contributor.author | Park, Kyung-Hwa | - |
dc.contributor.author | Choi, Won Suk | - |
dc.contributor.author | Cheong, Hee Jin | - |
dc.contributor.author | Kim, Woo Joo | - |
dc.date.accessioned | 2021-09-02T02:12:50Z | - |
dc.date.available | 2021-09-02T02:12:50Z | - |
dc.date.created | 2021-06-19 | - |
dc.date.issued | 2018-12-06 | - |
dc.identifier.issn | 1932-6203 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/71230 | - |
dc.description.abstract | Background Influenza and pneumonia are leading causes of morbidity and mortality among the elderly. Although vaccination is a main strategy to prevent these infectious diseases, concerns remain with respect to vaccine effectiveness. Methods During three influenza seasons (2014-2015, 2015-2016 and 2016-2017), we evaluated the effectiveness of the influenza and pneumococcal vaccines against pneumonia and acute exacerbation of cardiopulmonary diseases among the elderly aged >= 65 years with influenza-like illness (ILI). Demographic and clinical data were collected prospectively. Results Among 2,119 enrolled cases, 1,302 (61.4%) and 871 (41.1%) received the influenza vaccine and 23-valent pneumococcal polysaccharide vaccine (PPV23), respectively. During an A/H3N2-dominant season with poor influenza vaccine effectiveness (2014-2015 season), neither the influenza vaccine nor PPV23 showed significant effectiveness against pneumonia or acute exacerbation of cardiopulmonary diseases. During seasons with good influenza vaccine effectiveness (2015-2016 and 2016-2017 seasons), the influenza vaccine was effective in preventing pneumonia, but PPV23 was not. In particular, the influenza vaccine was effective in preventing acute exacerbation of heart diseases (75.0%) during the A/H1N1-dominant 2015-2016 season. Conclusion The influenza vaccine was effective in preventing pneumonia only during vaccine-matched seasons with good effectiveness against circulating influenza viruses. In addition, the influenza vaccine was cardio-protective during a vaccine-matched A/H1N1-dominant season. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | PUBLIC LIBRARY SCIENCE | - |
dc.subject | NATIONAL IMMUNIZATION PROGRAM | - |
dc.subject | COMMUNITY-ACQUIRED PNEUMONIA | - |
dc.subject | PREVENTING HOSPITALIZATION | - |
dc.subject | KOREA | - |
dc.subject | SURVEILLANCE | - |
dc.subject | ASSOCIATION | - |
dc.subject | POPULATION | - |
dc.subject | IMPACT | - |
dc.subject | VIRUS | - |
dc.subject | OLDER | - |
dc.title | Effectiveness of influenza and pneumococcal polysaccharide vaccines against influenza-related outcomes including pneumonia and acute exacerbation of cardiopulmonary diseases: Analysis by dominant viral subtype and vaccine matching | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Song, Joon Young | - |
dc.contributor.affiliatedAuthor | Choi, Won Suk | - |
dc.contributor.affiliatedAuthor | Kim, Woo Joo | - |
dc.identifier.doi | 10.1371/journal.pone.0207918 | - |
dc.identifier.scopusid | 2-s2.0-85057739685 | - |
dc.identifier.wosid | 000452307600023 | - |
dc.identifier.bibliographicCitation | PLOS ONE, v.13, no.12 | - |
dc.relation.isPartOf | PLOS ONE | - |
dc.citation.title | PLOS ONE | - |
dc.citation.volume | 13 | - |
dc.citation.number | 12 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalWebOfScienceCategory | Multidisciplinary Sciences | - |
dc.subject.keywordPlus | NATIONAL IMMUNIZATION PROGRAM | - |
dc.subject.keywordPlus | COMMUNITY-ACQUIRED PNEUMONIA | - |
dc.subject.keywordPlus | PREVENTING HOSPITALIZATION | - |
dc.subject.keywordPlus | KOREA | - |
dc.subject.keywordPlus | SURVEILLANCE | - |
dc.subject.keywordPlus | ASSOCIATION | - |
dc.subject.keywordPlus | POPULATION | - |
dc.subject.keywordPlus | IMPACT | - |
dc.subject.keywordPlus | VIRUS | - |
dc.subject.keywordPlus | OLDER | - |
dc.subject.keywordAuthor | pneumococcal vaccine | - |
dc.subject.keywordAuthor | influenza vaccine | - |
dc.subject.keywordAuthor | effectiveness | - |
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