Iodine-Promoted One-pot Synthesis of Highly Substituted 4-Aminopyrroles and Bis-4-aminopyrrole from Aryl Methyl Ketones, Arylamines, and Enamines
DC Field | Value | Language |
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dc.contributor.author | Jalani, Hitesh B. | - |
dc.contributor.author | Mali, Jyotirling R. | - |
dc.contributor.author | Park, Hyejun | - |
dc.contributor.author | Lee, Jae Kyun | - |
dc.contributor.author | Lee, Kiho | - |
dc.contributor.author | Lee, Kyeong | - |
dc.contributor.author | Choi, Yongseok | - |
dc.date.accessioned | 2021-09-02T04:03:30Z | - |
dc.date.available | 2021-09-02T04:03:30Z | - |
dc.date.created | 2021-06-19 | - |
dc.date.issued | 2018-11-05 | - |
dc.identifier.issn | 1615-4150 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/71885 | - |
dc.description.abstract | An iodine-promoted one-pot synthesis of functionally diverse and highly substituted 4-aminopyrroles directly from aryl methyl ketones, arylamines, and enamines was developed. The reaction involves in-situ oxidation of aryl methyl ketone to glyoxal, subsequent imine formation by aniline, followed by nucleophilic addition of enamine, and cyclization to afford highly substituted 4-aminopyrroles. This reaction involved the formation of two C-N bonds and one C-C bond by a formal [1+1+3] annulation approach. The present method provides an interesting framework of two 4-aminopyrrole units directly attached to a biphenyl core by the reaction of 4,4 '-diacyl biphenyl, amine, and enamine groups. This Hantzsch-type one-pot reaction provides diverse 4-aminopyrroles, which could be useful in medicinal/material chemistry. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | WILEY-V C H VERLAG GMBH | - |
dc.subject | EFFICIENT SYNTHESIS | - |
dc.subject | DOMINO REACTION | - |
dc.subject | FUSED PYRROLES | - |
dc.subject | PYRIMIDINES | - |
dc.subject | DERIVATIVES | - |
dc.subject | ALKALOIDS | - |
dc.subject | OXIDATION | - |
dc.subject | ANILINES | - |
dc.title | Iodine-Promoted One-pot Synthesis of Highly Substituted 4-Aminopyrroles and Bis-4-aminopyrrole from Aryl Methyl Ketones, Arylamines, and Enamines | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lee, Kiho | - |
dc.contributor.affiliatedAuthor | Choi, Yongseok | - |
dc.identifier.doi | 10.1002/adsc.201800899 | - |
dc.identifier.scopusid | 2-s2.0-85053623083 | - |
dc.identifier.wosid | 000449688000008 | - |
dc.identifier.bibliographicCitation | ADVANCED SYNTHESIS & CATALYSIS, v.360, no.21, pp.4073 - 4079 | - |
dc.relation.isPartOf | ADVANCED SYNTHESIS & CATALYSIS | - |
dc.citation.title | ADVANCED SYNTHESIS & CATALYSIS | - |
dc.citation.volume | 360 | - |
dc.citation.number | 21 | - |
dc.citation.startPage | 4073 | - |
dc.citation.endPage | 4079 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Applied | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Organic | - |
dc.subject.keywordPlus | EFFICIENT SYNTHESIS | - |
dc.subject.keywordPlus | DOMINO REACTION | - |
dc.subject.keywordPlus | FUSED PYRROLES | - |
dc.subject.keywordPlus | PYRIMIDINES | - |
dc.subject.keywordPlus | DERIVATIVES | - |
dc.subject.keywordPlus | ALKALOIDS | - |
dc.subject.keywordPlus | OXIDATION | - |
dc.subject.keywordPlus | ANILINES | - |
dc.subject.keywordAuthor | 4-Aminopyrroles | - |
dc.subject.keywordAuthor | Kornblum oxidation | - |
dc.subject.keywordAuthor | Enamines | - |
dc.subject.keywordAuthor | Hantzsch-type one-pot approach | - |
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