Role of non-classical T cells in skin immunity
DC Field | Value | Language |
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dc.contributor.author | Park, Joon Seok | - |
dc.contributor.author | Kim, Ji Hyung | - |
dc.date.accessioned | 2021-09-02T04:24:19Z | - |
dc.date.available | 2021-09-02T04:24:19Z | - |
dc.date.created | 2021-06-19 | - |
dc.date.issued | 2018-11 | - |
dc.identifier.issn | 0161-5890 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/72062 | - |
dc.description.abstract | The immune network controls homeostasis and inflammation of the skin. Immune cells use their antigen receptors to respond to a wide range of insults originating from microbes and allergens. T cells, which are key effector cells in the immune system, engage their T cell receptors (TCRs) to recognize self and foreign antigens in the context of classical major histocompatibility complex (MHC) molecules, MHC-like CD1 proteins, or MHC class I-related molecules. Recently, increasing evidence has demonstrated that T cells activated by non-canonical antigens are important in skin diseases. This review focuses on recent studies examining the roles of non-classical antigen-presenting molecules and their reactive T cells in the skin immune system. Additionally, we describe the types of ligands that activate these unconventional T cells through the non-classical MHC pathway. Finally, we highlight recent advances in the understanding of the physiological functions of non-classical T cells in the skin. Further investigation may result in the development of new therapeutic strategies for treating immune-related skin diseases. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | PERGAMON-ELSEVIER SCIENCE LTD | - |
dc.subject | ANTIGEN PRESENTATION | - |
dc.subject | LANGERHANS CELLS | - |
dc.subject | MAIT CELLS | - |
dc.subject | NKT CELLS | - |
dc.subject | PSORIASIFORM DERMATITIS | - |
dc.subject | NONPEPTIDE ANTIGENS | - |
dc.subject | CRYSTAL-STRUCTURE | - |
dc.subject | DENDRITIC CELLS | - |
dc.subject | RECOGNITION | - |
dc.subject | CD1D | - |
dc.title | Role of non-classical T cells in skin immunity | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Ji Hyung | - |
dc.identifier.doi | 10.1016/j.molimm.2018.09.024 | - |
dc.identifier.scopusid | 2-s2.0-85055031045 | - |
dc.identifier.wosid | 000450382400032 | - |
dc.identifier.bibliographicCitation | MOLECULAR IMMUNOLOGY, v.103, pp.286 - 292 | - |
dc.relation.isPartOf | MOLECULAR IMMUNOLOGY | - |
dc.citation.title | MOLECULAR IMMUNOLOGY | - |
dc.citation.volume | 103 | - |
dc.citation.startPage | 286 | - |
dc.citation.endPage | 292 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Immunology | - |
dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
dc.relation.journalWebOfScienceCategory | Immunology | - |
dc.subject.keywordPlus | ANTIGEN PRESENTATION | - |
dc.subject.keywordPlus | LANGERHANS CELLS | - |
dc.subject.keywordPlus | MAIT CELLS | - |
dc.subject.keywordPlus | NKT CELLS | - |
dc.subject.keywordPlus | PSORIASIFORM DERMATITIS | - |
dc.subject.keywordPlus | NONPEPTIDE ANTIGENS | - |
dc.subject.keywordPlus | CRYSTAL-STRUCTURE | - |
dc.subject.keywordPlus | DENDRITIC CELLS | - |
dc.subject.keywordPlus | RECOGNITION | - |
dc.subject.keywordPlus | CD1D | - |
dc.subject.keywordAuthor | Non-classical major histocompatibility complex molecules | - |
dc.subject.keywordAuthor | Unconventional T cell | - |
dc.subject.keywordAuthor | Lipid antigen | - |
dc.subject.keywordAuthor | Non-peptidyl antigen presentation | - |
dc.subject.keywordAuthor | Skin inflammation | - |
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