Value of CT added to ultrasonography for the diagnosis of lymph node metastasis in patients with thyroid cancer
- Authors
- Lee, Younghen; Kim, Ji-hoon; Baek, Jung Hwan; Jung, So Lyung; Park, Sun-Won; Kim, Jinna; Yun, Tae Jin; Ha, Eun Ju; Lee, Kyu Eun; Kwon, Soon Young; Yang, Kyung-Sook; Na, Dong Gyu
- Issue Date
- 10월-2018
- Publisher
- WILEY
- Keywords
- CT; lymph node; metastasis; thyroid cancer; ultrasonography
- Citation
- HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, v.40, no.10, pp.2137 - 2148
- Indexed
- SCIE
SCOPUS
- Journal Title
- HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
- Volume
- 40
- Number
- 10
- Start Page
- 2137
- End Page
- 2148
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/72552
- DOI
- 10.1002/hed.25202
- ISSN
- 1043-3074
- Abstract
- Background The benefit of CT for the diagnosis of lymph node metastasis in patients with thyroid cancer is still unclear. MethodsResultsThree hundred fifty-one patients with thyroid cancers from 7 hospitals were prospectively enrolled in order to compare diagnostic performance between a combination of ultrasound and CT (ultrasound/CT) and ultrasound alone for prediction of lymph node metastasis and to calculate patient-based benefits of CT added to ultrasound. Of 801 pathologically proven neck levels, ultrasound/CT showed higher sensitivities in both central and lateral compartments and improved accuracy in the lateral compartment compared to ultrasound alone. In the retropharyngeal/superior mediastinal compartment, although CT could detect lymph node metastasis an ultrasound could not. Patient-based benefit was demonstrated in 13.1% of patients (46/351), and was higher in patients with cancers >1 cm than cancers 1 cm. ConclusionIn patients with thyroid cancer, CT improved surgical planning by enhancing the sensitivity for lymph node metastasis and by detecting lymph node metastasis that was overlooked with ultrasound alone.
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Collections - College of Medicine > Department of Medical Science > 1. Journal Articles
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