The first case of congenital blood chimerism in two of the triplets in Korea
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Chung, Yoo Na | - |
dc.contributor.author | Chun, Sejong | - |
dc.contributor.author | Minh-Trang Thi Phan | - |
dc.contributor.author | Nam, Myung-Hyun | - |
dc.contributor.author | Choi, Byung Min | - |
dc.contributor.author | Cho, Duck | - |
dc.contributor.author | Choi, Ji Seon | - |
dc.date.accessioned | 2021-09-02T05:30:38Z | - |
dc.date.available | 2021-09-02T05:30:38Z | - |
dc.date.created | 2021-06-19 | - |
dc.date.issued | 2018-10 | - |
dc.identifier.issn | 0887-8013 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/72631 | - |
dc.description.abstract | BackgroundMethodsChimeras are composed of two or more different populations that originated from different zygotes. Blood chimerism arising from twins have been reported in the literature. Herein, we report the first blood group chimerism in triplets. ABO blood grouping was carried out by manual tile methods (Merck Millipore, UK) and micro-column agglutination method (Bio-Rad, Cressier sur Morat, Switzerland). Flow cytometric analysis was performed with Anti-A-PE conjugated monoclonal antibodies (BD Biosciences, San Jose, CA, USA) and FACS Canto II (BD Biosciences). Molecular analysis was performed with allele-specific polymerase chain reaction (AS-PCR) and direct sequencing of the exons 6 and 7. ResultsConclusionMixed-field agglutination and weak agglutination against anti-A were revealed by ABO blood grouping. Flow cytometric analysis revealed the presence of both A cells and O cells. AS-PCR and sequencing showed two neonates with chimerism, with each neonate`s genotype being A102/O01/O02. This is the first recorded case of blood chimera from a triplet in Korea. We recommend full investigation of blood group chimerism in neonates with ABO discrepancy, as blood chimerism is subject to certain caution in the clinical environment. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | WILEY | - |
dc.subject | MONOCHORIONIC DIZYGOTIC TWINS | - |
dc.subject | DATABASE | - |
dc.title | The first case of congenital blood chimerism in two of the triplets in Korea | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Nam, Myung-Hyun | - |
dc.contributor.affiliatedAuthor | Choi, Byung Min | - |
dc.identifier.doi | 10.1002/jcla.22580 | - |
dc.identifier.scopusid | 2-s2.0-85047502466 | - |
dc.identifier.wosid | 000447772900018 | - |
dc.identifier.bibliographicCitation | JOURNAL OF CLINICAL LABORATORY ANALYSIS, v.32, no.8 | - |
dc.relation.isPartOf | JOURNAL OF CLINICAL LABORATORY ANALYSIS | - |
dc.citation.title | JOURNAL OF CLINICAL LABORATORY ANALYSIS | - |
dc.citation.volume | 32 | - |
dc.citation.number | 8 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Medical Laboratory Technology | - |
dc.relation.journalWebOfScienceCategory | Medical Laboratory Technology | - |
dc.subject.keywordPlus | MONOCHORIONIC DIZYGOTIC TWINS | - |
dc.subject.keywordPlus | DATABASE | - |
dc.subject.keywordAuthor | allele-specific polymerase chain reaction (AS-PCR) | - |
dc.subject.keywordAuthor | blood chimerism | - |
dc.subject.keywordAuthor | direct sequencing | - |
dc.subject.keywordAuthor | flow cytometric analysis | - |
dc.subject.keywordAuthor | triplets | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(02841) 서울특별시 성북구 안암로 14502-3290-1114
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.