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Recent update of the 2017 Korean Association for the Study of the Liver (KASL) treatment guidelines of chronic hepatitis C: Comparison of guidelines from other continents, 2017 AASLD/IDSA and 2016 EASL

Authors
Yeon, Jong Eun
Issue Date
9월-2018
Publisher
KOREAN ASSOC STUDY LIVER
Keywords
Hepatitis C virus; Direct acting antiviral; Resistance associated substitutions; Genotype; Liver cirrhosis
Citation
CLINICAL AND MOLECULAR HEPATOLOGY, v.24, no.3, pp.278 - 293
Indexed
SCOPUS
KCI
Journal Title
CLINICAL AND MOLECULAR HEPATOLOGY
Volume
24
Number
3
Start Page
278
End Page
293
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/73195
DOI
10.3350/cmh.2018.1002
ISSN
2287-2728
Abstract
The paradigm for the treatment of chronic hepatitis C (CHC) has been changed due to the development of direct acting antivirals (DAAs) of hepatitis C virus (HCV). The high sustained virologic response rate and ease of administration makes the DAAs approach ideal to contribute to the complete eradication of HCV. Currently, treatment options for individual patients vary depending on the genotype or subtype of HCV, presence or absence of liver cirrhosis, previous experience of antiviral treatment or resistance associated substitutions. Because of drug avalilability, cost-effectiveness, preference, compliance and greater possibility of desirable effects and presumed patient-important outcomes may vary between countries, treatment options for individual patients are different. The review focuses on the comparing the current treatment options for CHC in other continents with the 2017 Korea Association for the Study of the Liver guidelines.
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