Development of a low flow-resistive charged nanoporous membrane in a microchip for fast electropreconcentration
- Authors
- Chun, Honggu
- Issue Date
- 9월-2018
- Publisher
- WILEY
- Keywords
- Electropreconcentration; Ion concentration polarization; Ion exchange membrane; lontronics; Microfluidics; Poly-SS
- Citation
- ELECTROPHORESIS, v.39, no.17, pp.2181 - 2187
- Indexed
- SCIE
SCOPUS
- Journal Title
- ELECTROPHORESIS
- Volume
- 39
- Number
- 17
- Start Page
- 2181
- End Page
- 2187
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/73235
- DOI
- 10.1002/elps.201800093
- ISSN
- 0173-0835
- Abstract
- A nanoporous poly-(styrene sulfonate) (poly-SS) membrane was developed for fast and selective ion transport in a microfluidic chip. The poly-SS membrane can be photopolymerized in-situ at arbitrary location of a microchannel, enabling integrated fluidics design in the microfluidic chip. The membrane is characterized by a low hydraulic resistance and a high surface charge to maximize the electroosmotic flow and charge selectivity. The membrane characteristics were investigated by charge-selective electropreconcentration method. Experimental results show membranes with various percentages of poly-SS are able to concentrate anions (fluorescein and TRITC-labeled BSA). The anion-selective electropreconcentration process is stable and 26-times faster than previously reported poly-AMPS (2-acrylamido-2-methyl-1-propanesulfonic acid) based system. The electropreconcentration was also demonstrated to depend on the sample valency and buffer concentration.
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Collections - Graduate School > Department of Bioengineering > 1. Journal Articles
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