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Is It Worth Treating Non-Bothering Nocturia? Results of a Multicenter Prospective Observational Study

Authors
Park, KwangsungPark, Hyoung KeunKim, Sae WoongYang, Dae YulPark, Jong KwanPark, Hyun JunMoon, Ki HakMoon, Du GeonMin, Kweon SikSon, HwancheolLee, Sung WonHyun, Jae SeogChoi, Woo SukYang, Sang-Kuk
Issue Date
9월-2018
Publisher
KOREAN SOC SEXUAL MEDICINE & ANDROLOGY
Keywords
Lower urinary tract symptoms; Nocturia; Prostatic hyperplasia; Therapeutics
Citation
WORLD JOURNAL OF MENS HEALTH, v.36, no.3, pp.248 - 254
Indexed
SCIE
KCI
Journal Title
WORLD JOURNAL OF MENS HEALTH
Volume
36
Number
3
Start Page
248
End Page
254
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/73281
DOI
10.5534/wjmh.170003
ISSN
2287-4208
Abstract
Purpose: The purpose of this study was to evaluate the efficacy of treatment in patients with non-bothering nocturia. Materials and Methods: In this prospective multicenter study, patients who visited hospitals for treatment of voiding symptoms were enrolled. Inclusion criteria were: 1) men >45 years, and 2) nocturia >= 2 confirmed by a three-day voiding diary. Subjects were divided into non-bothering and bothering groups based on International Consultation on Incontinence Questionnaire Nocturia (ICIQ-N) question 2b. Changes in voiding symptoms, frequency of nocturia, and bothersomeness were evaluated with international prostate symptom score (IPSS), ICIQ-N, and three-day voiding diary at 4 and 12 weeks after treatment. Results: A total of 48 patients in the non-bothering nocturia group and 50 patients in the bothering nocturia group who completed the 12-week treatment were analyzed. The total IPSS was decreased by 5.8 in the non-bothering group and 5.2 in the bothering group. There was no significant difference in decrease of IPSS between the two groups. Both groups showed significant reduction in discomfort of nocturia. The ICIQ-N 2b score decreased from 3.9 to 2.7 (p=0.01) in the non-bothering group and from 6.9 to 4.6 (p=0.02) in the bothering group. The number of nocturia episodes was significantly decreased in both groups. Conclusions: Regardless of discomfort associated with nocturia, both groups showed significant improvement in nocturia-related discomfort and voiding symptoms. These results suggest that patients with nocturia who were unaware of its discomfort benefited from treatment.
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