Lid Wiper Epitheliopathy in Patients with Dry Eye Refractory to Conventional Medical Treatment
- Authors
- Huh, Jungah; Woo, In Ho; Eom, Youngsub; Kang, Su-Yeon; Kim, Hyo Myung; Song, Jong-Suk
- Issue Date
- 8월-2018
- Publisher
- KOREAN OPHTHALMOLOGICAL SOC
- Keywords
- Correlation; Dry eye; Lid wiper epitheliopathy; Medical; Refractory
- Citation
- JOURNAL OF THE KOREAN OPHTHALMOLOGICAL SOCIETY, v.59, no.8, pp.718 - 723
- Indexed
- SCOPUS
KCI
- Journal Title
- JOURNAL OF THE KOREAN OPHTHALMOLOGICAL SOCIETY
- Volume
- 59
- Number
- 8
- Start Page
- 718
- End Page
- 723
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/73889
- DOI
- 10.3341/jkos.2018.59.8.718
- ISSN
- 0378-6471
- Abstract
- Purpose: We evaluated the effects of lid wiper epitheliopathy on the clinical manifestations of dry eye in patients refractory to conventional medical treatment. Methods: Forty-six patients (46 eyes) completed the subjective Ocular Surface Disease Index (OSDI), and we obtained objective measures including the tear break-up time (TBUT), the National Eye Institute (NEI) corneal staining score, tear osmolarity, and lid wiper epitheliopathy as revealed on photographs taken using a yellow filter after fluorescein instillation. The images were graded using the Korb B protocol. Results: The mean OSDI score was 48.06 +/- 21.19; 34 patients (73.9%) were had scores >= 33. Lid wiper epitheliopathy was evident in 41 (89.1%), and the epitheliopathy grade and OSDI score were correlated (r = 0.56, p < 0.01). The NEI score was also positively correlated with the OSDI score (r = 0.54, p < 0.01), but the mean value was low (1.59 +/- 2.13). The OSDI score did not correlate significantly with either the TBUT or tear osmolarity (r = -0.16, p = 0.279; r = 0.16, p = 0.298, respectively). Conclusions: Lid wiper epitheliopathy was present in about 90% of patients with dry eye who visited our tertiary hospital, and a significant correlation was evident between the epitheliopathy grade and the OSDI score.
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Collections - College of Medicine > Department of Medical Science > 1. Journal Articles
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