A low-noise silicon nitride nanopore device on a polymer substrate
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Choi, Wook | - |
dc.contributor.author | Jeon, Eun-Seok | - |
dc.contributor.author | Chun, Kyoung-Yong | - |
dc.contributor.author | Kim, Young-Rok | - |
dc.contributor.author | Park, Kyeong-Beom | - |
dc.contributor.author | Kim, Ki-Bum | - |
dc.contributor.author | Han, Chang-Soo | - |
dc.date.accessioned | 2021-09-02T08:54:21Z | - |
dc.date.available | 2021-09-02T08:54:21Z | - |
dc.date.created | 2021-06-16 | - |
dc.date.issued | 2018-07-20 | - |
dc.identifier.issn | 1932-6203 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/74317 | - |
dc.description.abstract | We report a novel low-noise nanopore device employing a polymer substrate. The Si substrate of a fabricated Si-substrate-based silicon nitride (Si3N4) membrane was replaced with a polymer substrate. As such, laser machining was used to make a micro-size hole through the polyimide (PI) substrate, and a thin Si3N4 membrane was then transferred onto the PI substrate. Finally, a nanopore was formed in the membrane using a transmission electron microscope for detection of biomolecules. Compared to the Si-substrate-based device, the dielectric noise was greatly reduced and the root-mean-square noise level was decreased from 146.7 to 5.4 pA. Using this device, the translocation of double-strand deoxyribonucleic acid (DNA) was detected with a high signal/noise (S/N) ratio. This type of device is anticipated to be available for future versatile sequencing technologies. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | PUBLIC LIBRARY SCIENCE | - |
dc.subject | SOLID-STATE NANOPORES | - |
dc.subject | DNA TRANSLOCATION | - |
dc.subject | SINGLE | - |
dc.subject | MEMBRANE | - |
dc.subject | IDENTIFICATION | - |
dc.subject | MOLECULES | - |
dc.subject | TRANSPORT | - |
dc.subject | DISCRIMINATION | - |
dc.subject | HOMOPOLYMERS | - |
dc.subject | PASSIVATION | - |
dc.title | A low-noise silicon nitride nanopore device on a polymer substrate | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Chun, Kyoung-Yong | - |
dc.contributor.affiliatedAuthor | Han, Chang-Soo | - |
dc.identifier.doi | 10.1371/journal.pone.0200831 | - |
dc.identifier.scopusid | 2-s2.0-85051824070 | - |
dc.identifier.wosid | 000439396900017 | - |
dc.identifier.bibliographicCitation | PLOS ONE, v.13, no.7 | - |
dc.relation.isPartOf | PLOS ONE | - |
dc.citation.title | PLOS ONE | - |
dc.citation.volume | 13 | - |
dc.citation.number | 7 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalWebOfScienceCategory | Multidisciplinary Sciences | - |
dc.subject.keywordPlus | SOLID-STATE NANOPORES | - |
dc.subject.keywordPlus | DNA TRANSLOCATION | - |
dc.subject.keywordPlus | SINGLE | - |
dc.subject.keywordPlus | MEMBRANE | - |
dc.subject.keywordPlus | IDENTIFICATION | - |
dc.subject.keywordPlus | MOLECULES | - |
dc.subject.keywordPlus | TRANSPORT | - |
dc.subject.keywordPlus | DISCRIMINATION | - |
dc.subject.keywordPlus | HOMOPOLYMERS | - |
dc.subject.keywordPlus | PASSIVATION | - |
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