Benefit of Prolonged Dual Antiplatelet Therapy After Implantation of Drug-Eluting Stent for Coronary Bifurcation Lesions Results From the Coronary Bifurcation Stenting Registry II
DC Field | Value | Language |
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dc.contributor.author | Jang, Woo Jin | - |
dc.contributor.author | Ahn, Sung Gyun | - |
dc.contributor.author | Song, Young Bin | - |
dc.contributor.author | Choi, Seung-Hyuk | - |
dc.contributor.author | Chun, Woo Jung | - |
dc.contributor.author | Oh, Ju Hyeon | - |
dc.contributor.author | Cho, Sung Woo | - |
dc.contributor.author | Kim, Bum Sung | - |
dc.contributor.author | Yoon, Jung Han | - |
dc.contributor.author | Koo, Bon-Kwon | - |
dc.contributor.author | Yu, Cheol Woong | - |
dc.contributor.author | Jang, Yang Soo | - |
dc.contributor.author | Tahk, Seung-Jea | - |
dc.contributor.author | Kim, Hyo-Soo | - |
dc.contributor.author | Gwon, Hyeon-Cheol | - |
dc.contributor.author | Lee, Sung Yun | - |
dc.contributor.author | Hahn, Joo-Yong | - |
dc.date.accessioned | 2021-09-02T09:51:16Z | - |
dc.date.available | 2021-09-02T09:51:16Z | - |
dc.date.created | 2021-06-16 | - |
dc.date.issued | 2018-07 | - |
dc.identifier.issn | 1941-7640 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/74834 | - |
dc.description.abstract | BACKGROUND: Whether prolonged dual antiplatelet therapy (DAPT) improves clinical outcomes after percutaneous coronary intervention for coronary bifurcation lesion is uncertain. METHODS AND RESULTS: We evaluated 2082 patients who were treated with drug-eluting stent for bifurcation lesions and were event free (no death, myocardial infarction [MI], cerebrovascular accident, stent thrombosis, or any revascularization) at 12 months after the index procedure. Patients were divided into 2 groups: DAPT >= 12-month group (n=1776) and DAPT <12-month group (n=306). Primary outcome was all-cause death or MI. At 4 years after the index procedure, death or MI occurred less frequently in the DAPT >= 12-month group than the DAPT <12-month group (2.8% versus 12.3%; adjusted hazard ratio, 0.21; 95% confidence interval, 0.13-0.35; P<0.001). After propensity score matching, incidence of death or MI was still lower in the DAPT >= 12-month group than the DAPT <12-month group (2.6% versus 12.3%; adjusted hazard ratio, 0.22; 95% confidence interval, 0.12-0.38; P<0.001). In subgroup analysis, the treatment effect of prolonged DAPT was consistent across subgroups regardless of lesion location, stenting technique, or type of used drug-eluting stent. CONCLUSIONS: The risk of all-cause death or MI was significantly lower in the >= 12-month DAPT group than the <12-month DAPT group after percutaneous coronary intervention for bifurcation lesion using drug-eluting stent. Our results suggest that prolonged DAPT may improve long-term clinical outcomes after percutaneous coronary intervention for bifurcation lesions. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | LIPPINCOTT WILLIAMS & WILKINS | - |
dc.subject | CLINICAL-OUTCOMES | - |
dc.subject | DURATION | - |
dc.subject | EFFICACY | - |
dc.subject | SAFETY | - |
dc.subject | MORTALITY | - |
dc.subject | TRIAL | - |
dc.title | Benefit of Prolonged Dual Antiplatelet Therapy After Implantation of Drug-Eluting Stent for Coronary Bifurcation Lesions Results From the Coronary Bifurcation Stenting Registry II | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Yu, Cheol Woong | - |
dc.identifier.doi | 10.1161/CIRCINTERVENTIONS.117.005849 | - |
dc.identifier.scopusid | 2-s2.0-85058309407 | - |
dc.identifier.wosid | 000438925300001 | - |
dc.identifier.bibliographicCitation | CIRCULATION-CARDIOVASCULAR INTERVENTIONS, v.11, no.7 | - |
dc.relation.isPartOf | CIRCULATION-CARDIOVASCULAR INTERVENTIONS | - |
dc.citation.title | CIRCULATION-CARDIOVASCULAR INTERVENTIONS | - |
dc.citation.volume | 11 | - |
dc.citation.number | 7 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Cardiovascular System & Cardiology | - |
dc.relation.journalWebOfScienceCategory | Cardiac & Cardiovascular Systems | - |
dc.subject.keywordPlus | CLINICAL-OUTCOMES | - |
dc.subject.keywordPlus | DURATION | - |
dc.subject.keywordPlus | EFFICACY | - |
dc.subject.keywordPlus | SAFETY | - |
dc.subject.keywordPlus | MORTALITY | - |
dc.subject.keywordPlus | TRIAL | - |
dc.subject.keywordAuthor | drug-eluting stents | - |
dc.subject.keywordAuthor | incidence | - |
dc.subject.keywordAuthor | myocardial infarction | - |
dc.subject.keywordAuthor | percutaneous coronary intervention | - |
dc.subject.keywordAuthor | thrombosis | - |
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