Sequence selective photoinduced electron transfer of a pyrene-porphyrin dyad to DNA
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Heo, Myeong Eun | - |
dc.contributor.author | Lee, Young-Ae | - |
dc.contributor.author | Hirakawa, Kazutaka | - |
dc.contributor.author | Okazaki, Shigetoshi | - |
dc.contributor.author | Kim, Seog K. | - |
dc.contributor.author | Cho, Dae Won | - |
dc.date.accessioned | 2021-09-02T10:03:36Z | - |
dc.date.available | 2021-09-02T10:03:36Z | - |
dc.date.created | 2021-06-16 | - |
dc.date.issued | 2018-06-28 | - |
dc.identifier.issn | 1463-9076 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/74887 | - |
dc.description.abstract | The binding modes of a pyrene-porphyrin dyad, (1-pyrenyl)-tris(N-methyl-p-pyridino) porphyrin (PyTMpyP), to various DNAs (calf thymus DNA (Ct-DNA), poly[d(G-C)(2)], and poly[d(A-T)(2)]) have been investigated using circular dichroism and linear dichroism measurements. Based on the polarization spectroscopic results, it can be shown that the pyrenyl and porphryin planes are skewed to a large extent for PyTMPyP in an aqueous environment and in the binding site of poly[d(G-C)(2)]. In this complex, a photoinduced electron transfer (PET) process between the pyrenyl and porphyrin moieties occurs. On the other hand, PET was not observed in the PyTMPyP-poly[d(A-T)(2)] complex, whereas the fluorescence intensity of TMPyP was enhanced. The molecular planes of the pyrene and porphyrin moieties are almost parallel in the poly[d(A-T)(2)] and Ct-DNA adducts. Moreover, the generation of O-1(2) species occurs only for the PyTMPyP-Ct-DNA and PyTMPyP-poly[d(A-T)(2)] complexes. We discuss the photophysical properties of PyTMPyP which are attributed to the binding patterns and the sequence of DNA bases. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | ROYAL SOC CHEMISTRY | - |
dc.subject | SINGLET OXYGEN | - |
dc.subject | BINDING MODE | - |
dc.subject | PHOTOCLEAVAGE PROPERTIES | - |
dc.subject | CATIONIC PORPHYRINS | - |
dc.subject | CIRCULAR-DICHROISM | - |
dc.subject | ENERGY-TRANSFER | - |
dc.subject | CELLULAR-DNA | - |
dc.subject | MESO-TETRAKIS(N-METHYLPYRIDINIUM-4-YL)PORPHYRIN | - |
dc.subject | GENERATION | - |
dc.subject | OXIDATION | - |
dc.title | Sequence selective photoinduced electron transfer of a pyrene-porphyrin dyad to DNA | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Cho, Dae Won | - |
dc.identifier.doi | 10.1039/c8cp01870g | - |
dc.identifier.scopusid | 2-s2.0-85048945424 | - |
dc.identifier.wosid | 000436032900008 | - |
dc.identifier.bibliographicCitation | PHYSICAL CHEMISTRY CHEMICAL PHYSICS, v.20, no.24, pp.16386 - 16392 | - |
dc.relation.isPartOf | PHYSICAL CHEMISTRY CHEMICAL PHYSICS | - |
dc.citation.title | PHYSICAL CHEMISTRY CHEMICAL PHYSICS | - |
dc.citation.volume | 20 | - |
dc.citation.number | 24 | - |
dc.citation.startPage | 16386 | - |
dc.citation.endPage | 16392 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Physics | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Physical | - |
dc.relation.journalWebOfScienceCategory | Physics, Atomic, Molecular & Chemical | - |
dc.subject.keywordPlus | SINGLET OXYGEN | - |
dc.subject.keywordPlus | BINDING MODE | - |
dc.subject.keywordPlus | PHOTOCLEAVAGE PROPERTIES | - |
dc.subject.keywordPlus | CATIONIC PORPHYRINS | - |
dc.subject.keywordPlus | CIRCULAR-DICHROISM | - |
dc.subject.keywordPlus | ENERGY-TRANSFER | - |
dc.subject.keywordPlus | CELLULAR-DNA | - |
dc.subject.keywordPlus | MESO-TETRAKIS(N-METHYLPYRIDINIUM-4-YL)PORPHYRIN | - |
dc.subject.keywordPlus | GENERATION | - |
dc.subject.keywordPlus | OXIDATION | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(02841) 서울특별시 성북구 안암로 14502-3290-1114
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.