Coextrusion-Based 3D Plotting of Ceramic Pastes for Porous Calcium Phosphate Scaffolds Comprised of Hollow Filaments
- Authors
- Jo, In-Hwan; Koh, Young-Hag; Kim, Hyoun-Ee
- Issue Date
- 6월-2018
- Publisher
- MDPI
- Keywords
- calcium phosphate; additive manufacturing; porous structure; mechanical properties; biocompatibility
- Citation
- MATERIALS, v.11, no.6
- Indexed
- SCIE
SCOPUS
- Journal Title
- MATERIALS
- Volume
- 11
- Number
- 6
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/75041
- DOI
- 10.3390/ma11060911
- ISSN
- 1996-1944
- Abstract
- This paper demonstrates the utility of coextrusion-based 3D plotting of ceramic pastes (CoEx-3DP) as a new type of additive manufacturing (AM) technique, which can produce porous calcium phosphate (CaP) ceramic scaffolds comprised of hollow CaP filaments. In this technique, green filaments with a controlled core/shell structure can be produced by coextruding an initial feedrod, comprised of the carbon black (CB) core and CaP shell, through a fine nozzle in an acetone bath and then deposited in a controlled manner according to predetermined paths. In addition, channels in CaP filaments can be created through the removal of the CB cores during heat-treatment. Produced CaP scaffolds had two different types of pores with well-defined geometries: three-dimensionally interconnected pores (similar to 360 x 230 m(2) in sizes) and channels (>100 m in diameter) in hollow CaP filaments. The porous scaffolds showed high compressive strengths of similar to 12.3 +/- 2.2 MPa at a high porosity of similar to 73 vol % when compressed parallel to the direction of the hollow CaP filaments. In addition, the mechanical properties of porous CaP scaffolds could be tailored by adjusting their porosity, for example, compressive strengths of 4.8 +/- 1.1 MPa at a porosity of similar to 82 vol %. The porous CaP scaffold showed good biocompatibility, which was assessed by in vitro cell tests, where several the cells adhered to and spread actively with the outer and inner surfaces of the hollow CaP filaments.
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