Cost-effectiveness of contact screening strategies for tuberculosis among high-school adolescents in South Korea
DC Field | Value | Language |
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dc.contributor.author | Sohn, H. | - |
dc.contributor.author | Kim, H-Y | - |
dc.contributor.author | Lee, S. H. | - |
dc.date.accessioned | 2021-09-02T11:55:25Z | - |
dc.date.available | 2021-09-02T11:55:25Z | - |
dc.date.created | 2021-06-19 | - |
dc.date.issued | 2018-05 | - |
dc.identifier.issn | 1027-3719 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/75690 | - |
dc.description.abstract | BACKGROUND: Effective latent tuberculous infection (LTBI) control among adolescents is a critical component of tuberculosis (TB) elimination in Korea. OBJECTIVE: To compare the cost-effectiveness of the following contact screening strategies for LTBI among high-school adolescents after TB outbreaks: Quanti-FERON (R)-TB Gold In-Tube (QFT-GIT), the tuberculin skin test (TST), or TST/QI-T-GIT (two-step strategy). METHOD: The costs of post-TB outbreak screening strategies were calculated using a mixed (top-down and bottom-up) cost analysis method and expressed in 2015 US dollars. Cost-effectiveness was evaluated using a decision analysis model from the health system perspective, comparing cumulative health care costs and the total number of TB cases averted. RESULTS: In a hypothetical cohort of 1000 students, screening using the TST-alone strategy averted 1.6 TB cases at a total cost of US$52 566. The QI-T-GIT-alone strategy helped avert 2.0 TB cases, but was associated with a much higher total cost (US$108 435), resulting in an incremental cost-effectiveness ratio of US$140 933/ TB case averted. The two-step TST/QFT-GIT strategy was worse than the TST-alone strategy, averting 1.3 TB cases at US$75 267. CONCLUSION: The TST-alone strategy was the most cost-effective; the QFT-GIT-alone strategy averted the greatest number of TB cases but incurred the highest cost in contact investigation for school TB outbreaks. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | INT UNION AGAINST TUBERCULOSIS LUNG DISEASE (I U A T L D) | - |
dc.subject | GAMMA RELEASE ASSAYS | - |
dc.subject | PULMONARY TUBERCULOSIS | - |
dc.subject | INCOME COUNTRIES | - |
dc.subject | SKIN-TEST | - |
dc.subject | INFECTION | - |
dc.subject | DIAGNOSIS | - |
dc.subject | CHILDREN | - |
dc.subject | GUIDELINES | - |
dc.subject | ADHERENCE | - |
dc.subject | DISEASE | - |
dc.title | Cost-effectiveness of contact screening strategies for tuberculosis among high-school adolescents in South Korea | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lee, S. H. | - |
dc.identifier.doi | 10.5588/ijtld.17.0718 | - |
dc.identifier.scopusid | 2-s2.0-85046288111 | - |
dc.identifier.wosid | 000435764500007 | - |
dc.identifier.bibliographicCitation | INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE, v.22, no.5, pp.496 - + | - |
dc.relation.isPartOf | INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE | - |
dc.citation.title | INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE | - |
dc.citation.volume | 22 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 496 | - |
dc.citation.endPage | + | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Infectious Diseases | - |
dc.relation.journalResearchArea | Respiratory System | - |
dc.relation.journalWebOfScienceCategory | Infectious Diseases | - |
dc.relation.journalWebOfScienceCategory | Respiratory System | - |
dc.subject.keywordPlus | GAMMA RELEASE ASSAYS | - |
dc.subject.keywordPlus | PULMONARY TUBERCULOSIS | - |
dc.subject.keywordPlus | INCOME COUNTRIES | - |
dc.subject.keywordPlus | SKIN-TEST | - |
dc.subject.keywordPlus | INFECTION | - |
dc.subject.keywordPlus | DIAGNOSIS | - |
dc.subject.keywordPlus | CHILDREN | - |
dc.subject.keywordPlus | GUIDELINES | - |
dc.subject.keywordPlus | ADHERENCE | - |
dc.subject.keywordPlus | DISEASE | - |
dc.subject.keywordAuthor | latent tuberculous infection | - |
dc.subject.keywordAuthor | contact screening | - |
dc.subject.keywordAuthor | QuantiFERON (R) test | - |
dc.subject.keywordAuthor | tuberculin skin test | - |
dc.subject.keywordAuthor | cost-effectiveness | - |
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