Validation of the eighth edition of the American Joint Committee on Cancer staging system for ampulla of Vater cancer
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Sung Joo | - |
dc.contributor.author | An, Soyeon | - |
dc.contributor.author | Kang, Hyo Jeong | - |
dc.contributor.author | Kim, Joo Young | - |
dc.contributor.author | Jang, Min Ah | - |
dc.contributor.author | Lee, Jae Hoon | - |
dc.contributor.author | Song, Ki-Byung | - |
dc.contributor.author | Hwang, Dae Wook | - |
dc.contributor.author | Cho, HyungJun | - |
dc.contributor.author | Kim, Song Cheol | - |
dc.contributor.author | Yu, Eunsil | - |
dc.contributor.author | Hong, Seung-Mo | - |
dc.date.accessioned | 2021-09-02T12:28:27Z | - |
dc.date.available | 2021-09-02T12:28:27Z | - |
dc.date.created | 2021-06-16 | - |
dc.date.issued | 2018-05 | - |
dc.identifier.issn | 0039-6060 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/76033 | - |
dc.description.abstract | Background: The American Joint Committee on Cancer recently proposed the eighth edition of cancer staging system. Validation studies are required to evaluate the prognostic stratification of ampulla of Vater cancer patients. Methods: In the study, 369 operatively resected patients with ampullary cancers were grouped based on the eighth T (T1a, limited to sphincter of Oddi; T1b, invasion to duodenal submucosa; T2, invasion to duodenal proper muscle; T3a, invasion to pancreas <= 0.5 cm; T3b, invasion to pancreas >0.5 cm; and T4, involvement of celiac axis or superior mesenteric artery) and N (N0, no nodal metastasis; N1, 1-3 nodal metastasis; and N2, >= 4 nodal metastasis) category of ampullary cancer staging. Results: Overall 5-year survival rates for T and N categories were as followed: T1a, 83%; T1b, 71%; T2, 46%; T3a, 48%; T3b, 28.5%, T4, 7% (P < .001); N0, 44.8%; N1, 20%; N2, 4% (P < .001). Pair-wise comparisons demonstrated significant differences between T1a-b (P = .005), T3a-T3b (P = .03), N0-N1 (P < .001), and N1-N2 (P = .007) tumors, but not between T1b-T2 (P = .20), T2-T3a (P = .84), and T3b-T4 (P = .17) lesions. Conclusion: The eighth edition T category for ampullary cancer does not stratify patients accurately with regard to prognosis. Modification of the current T category with eliminating subcategories (T1, invasion to duodenal submucosa; T2, invasion to duodenal proper muscle; T3, invasion to pancreas or duodenal subserosa) is a better way for determining prognosis of ampullary cancer. The current N category segregates patient survival well. (C) 2017 Elsevier Inc. All rights reserved. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | MOSBY-ELSEVIER | - |
dc.subject | PROGNOSTIC-FACTORS | - |
dc.subject | LYMPH-NODES | - |
dc.subject | CARCINOMA | - |
dc.subject | ADENOCARCINOMA | - |
dc.subject | NUMBER | - |
dc.subject | RESECTION | - |
dc.subject | SURVIVAL | - |
dc.title | Validation of the eighth edition of the American Joint Committee on Cancer staging system for ampulla of Vater cancer | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Cho, HyungJun | - |
dc.identifier.doi | 10.1016/j.surg.2017.12.018 | - |
dc.identifier.scopusid | 2-s2.0-85041966676 | - |
dc.identifier.wosid | 000431940600016 | - |
dc.identifier.bibliographicCitation | SURGERY, v.163, no.5, pp.1071 - 1079 | - |
dc.relation.isPartOf | SURGERY | - |
dc.citation.title | SURGERY | - |
dc.citation.volume | 163 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 1071 | - |
dc.citation.endPage | 1079 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Surgery | - |
dc.relation.journalWebOfScienceCategory | Surgery | - |
dc.subject.keywordPlus | PROGNOSTIC-FACTORS | - |
dc.subject.keywordPlus | LYMPH-NODES | - |
dc.subject.keywordPlus | CARCINOMA | - |
dc.subject.keywordPlus | ADENOCARCINOMA | - |
dc.subject.keywordPlus | NUMBER | - |
dc.subject.keywordPlus | RESECTION | - |
dc.subject.keywordPlus | SURVIVAL | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(02841) 서울특별시 성북구 안암로 14502-3290-1114
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.