Longitudinal association between egg consumption and the risk of cardiovascular disease: interaction with type 2 diabetes mellitus
DC Field | Value | Language |
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dc.contributor.author | Jang, Jiyoung | - |
dc.contributor.author | Shin, Min-Jeong | - |
dc.contributor.author | Kim, Oh Yoen | - |
dc.contributor.author | Park, Kyong | - |
dc.date.accessioned | 2021-09-02T12:36:29Z | - |
dc.date.available | 2021-09-02T12:36:29Z | - |
dc.date.created | 2021-06-16 | - |
dc.date.issued | 2018-04-25 | - |
dc.identifier.issn | 2044-4052 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/76097 | - |
dc.description.abstract | Background/objectives: It remains unclear if high egg consumption has beneficial or adverse effects on cardiometabolic health. The present study prospectively evaluated the longitudinal association between egg-consumption levels and incident cardiovascular disease (CVD) among Korean adults. Subjects/methods: We conducted a prospective cohort study of 9248 Korean adults aged 40-69 years without CVD or cancer at the baseline from the Korean Genome and Epidemiology Study, Ansung-Ansan cohort, South Korea. The egg intake of the participants was estimated using a validated semiquantitative food frequency questionnaire at the baseline and the second follow-up examination and categorized into quartiles. CVD cases were identified using biennial questionnaires and confirmed through repeated in-depth personal interviews. Hazard ratios (HR) and 95% confidence interval (CI) were analyzed using Cox proportional hazard regression. Results: During the average follow-up of 7.3 years, 570 cases of CVD were newly diagnosed. After adjusting for multiple confounding variables, egg-intake levels were not associated with CVD incidence (HR: 1.14, 95% CI: 0.87-1.49, P for trend: 0.7). However, the association was modified by type 2 diabetes mellitus (T2DM) status. Egg consumption was significantly associated with an increased risk for incident CVD among participants with T2DM; individuals with the highest egg intake (4.2 +/- 0.04 eggs/week) had a 2.8 times higher incidence of CVD (HR: 2.81, 95% CI: 1.25-6.30, P for trend: 0.02) than those with the lowest egg intake (0.1 +/- 0.02 eggs/week). However, no association was observed among individuals without T2DM (HR: 1.03, 95% CI: 0.77-1.38, P for trend: 0.8). Conclusions: Higher egg consumption may increase the risk for CVD in Korean patients with T2DM. Our findings provide a basis for the development of an optimal dietary cholesterol intake guideline for the Korean population. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | NATURE PUBLISHING GROUP | - |
dc.subject | DIETARY-CHOLESTEROL | - |
dc.subject | METAANALYSIS | - |
dc.subject | PLASMA | - |
dc.title | Longitudinal association between egg consumption and the risk of cardiovascular disease: interaction with type 2 diabetes mellitus | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Shin, Min-Jeong | - |
dc.identifier.doi | 10.1038/s41387-018-0033-1 | - |
dc.identifier.scopusid | 2-s2.0-85046079783 | - |
dc.identifier.wosid | 000431723000003 | - |
dc.identifier.bibliographicCitation | NUTRITION & DIABETES, v.8 | - |
dc.relation.isPartOf | NUTRITION & DIABETES | - |
dc.citation.title | NUTRITION & DIABETES | - |
dc.citation.volume | 8 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Endocrinology & Metabolism | - |
dc.relation.journalResearchArea | Nutrition & Dietetics | - |
dc.relation.journalWebOfScienceCategory | Endocrinology & Metabolism | - |
dc.relation.journalWebOfScienceCategory | Nutrition & Dietetics | - |
dc.subject.keywordPlus | DIETARY-CHOLESTEROL | - |
dc.subject.keywordPlus | METAANALYSIS | - |
dc.subject.keywordPlus | PLASMA | - |
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