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Effect of various shaped magnesium hydroxide particles on mechanical and biological properties of poly(lactic-co-glycolic acid) composites

Authors
Jang, Hye JungPark, Sung-BinBedair, Tarek M.Oh, Min-KyuAhn, Dong-JunePark, WooramJoung, Yoon KiHan, Dong Keun
Issue Date
25-3월-2018
Publisher
ELSEVIER SCIENCE INC
Keywords
Magnesium hydroxide; Poly(lactic-co-glycolic acid) composites; Mechanical property; Anti-inflammation effect; Anti-bacterial activity
Citation
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY, v.59, pp.266 - 276
Indexed
SCIE
SCOPUS
KCI
Journal Title
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
Volume
59
Start Page
266
End Page
276
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/76692
DOI
10.1016/j.jiec.2017.10.032
ISSN
1226-086X
Abstract
Five different shapes of magnesium hydroxide (Mg(OH)(2)) particles (Plate-S, Plate-N, Disk, Whisker, and Fiber) were synthesized and added to biopolymer (i.e., Poly(lactic-co-glycolic acid) (PLGA)) composite to improve their mechanical and biological properties. The PLGA composite films including Mg(OH)(2) particles were prepared by a solvent casting method. Their mechanical and biological properties were compared according to the composites containing different shapes of Mg(OH)(2) particles. Among them; the fiber shape of Mg(OH)(2) provided the highest mechanical strength, and anti-inflammation and antibacterial activity to PLGA films among other forms. This study demonstrated a new strategy for the design of biomaterials by controlling the form of inorganic additives. (C) 2017 The Korean Society of Industrial and Engineering Chemistry. Published by Elsevier B.V. All rights reserved.
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Ahn, Dong June
공과대학 (화공생명공학과)
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