Continuous flow reaction system for the synthesis of 2,2,2-trichloroacetophenone derivatives and its application
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Ko, Byeng Ha | - |
dc.contributor.author | Yu, Subeen | - |
dc.contributor.author | Song, Kwang Ho | - |
dc.contributor.author | Lee, Sunwoo | - |
dc.date.accessioned | 2021-09-02T13:47:37Z | - |
dc.date.available | 2021-09-02T13:47:37Z | - |
dc.date.created | 2021-06-16 | - |
dc.date.issued | 2018-03-14 | - |
dc.identifier.issn | 0040-4039 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/76735 | - |
dc.description.abstract | A continuous flow reaction system was developed for the synthesis of 2,2,2-trichloroacetophenone derivatives. When aryl propiolic acids and water were mixed with trichloroisocyanuric acid in DMF at 5 degrees C, the 2,2,2-trichloroacetophenone derivatives were formed within 5 min with good yields. In addition, the resulting mixture was flowed to react with amines to give the corresponding benzamide. This flow reaction system provided higher yields within shorter times than the batch reaction system. (C) 2018 Elsevier Ltd. All rights reserved. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | PERGAMON-ELSEVIER SCIENCE LTD | - |
dc.subject | REACTION-TIME CONTROL | - |
dc.subject | TRICHLOROMETHYL COMPOUNDS | - |
dc.subject | CHEMISTRY | - |
dc.subject | OXIDATION | - |
dc.subject | PRODUCTS | - |
dc.subject | KETONES | - |
dc.subject | BATCH | - |
dc.subject | ACID | - |
dc.title | Continuous flow reaction system for the synthesis of 2,2,2-trichloroacetophenone derivatives and its application | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Song, Kwang Ho | - |
dc.identifier.doi | 10.1016/j.tetlet.2018.01.067 | - |
dc.identifier.scopusid | 2-s2.0-85041517480 | - |
dc.identifier.wosid | 000427217400007 | - |
dc.identifier.bibliographicCitation | TETRAHEDRON LETTERS, v.59, no.11, pp.991 - 994 | - |
dc.relation.isPartOf | TETRAHEDRON LETTERS | - |
dc.citation.title | TETRAHEDRON LETTERS | - |
dc.citation.volume | 59 | - |
dc.citation.number | 11 | - |
dc.citation.startPage | 991 | - |
dc.citation.endPage | 994 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Organic | - |
dc.subject.keywordPlus | REACTION-TIME CONTROL | - |
dc.subject.keywordPlus | TRICHLOROMETHYL COMPOUNDS | - |
dc.subject.keywordPlus | CHEMISTRY | - |
dc.subject.keywordPlus | OXIDATION | - |
dc.subject.keywordPlus | PRODUCTS | - |
dc.subject.keywordPlus | KETONES | - |
dc.subject.keywordPlus | BATCH | - |
dc.subject.keywordPlus | ACID | - |
dc.subject.keywordAuthor | Flow chemistry | - |
dc.subject.keywordAuthor | Trichloroacetophenone | - |
dc.subject.keywordAuthor | Decarboxylative chlorination | - |
dc.subject.keywordAuthor | Propiolic acid | - |
dc.subject.keywordAuthor | Trichloroisocyanuric acid | - |
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