Five-year major clinical outcomes according to severity of coronary artery spasm as assessed by intracoronary acetylcholine provocation test
DC Field | Value | Language |
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dc.contributor.author | Kim, Yong Hoon | - |
dc.contributor.author | Her, Ae-Young | - |
dc.contributor.author | Rha, Seung-Woon | - |
dc.contributor.author | Choi, Byoung Geol | - |
dc.contributor.author | Shim, Minsuk | - |
dc.contributor.author | Choi, Se Yeon | - |
dc.contributor.author | Byun, Jae Kyeong | - |
dc.contributor.author | Li, Hu | - |
dc.contributor.author | Kim, Woohyeun | - |
dc.contributor.author | Kang, Jun Hyuk | - |
dc.contributor.author | Choi, Jah Yeon | - |
dc.contributor.author | Park, Eun Jin | - |
dc.contributor.author | Park, Sung Hun | - |
dc.contributor.author | Lee, Sunki | - |
dc.contributor.author | Na, Jin Oh | - |
dc.contributor.author | Choi, Cheol Ung | - |
dc.contributor.author | Lim, Hong Euy | - |
dc.contributor.author | Kim, Eung Ju | - |
dc.contributor.author | Park, Chang Gyu | - |
dc.contributor.author | Seo, Hong Seog | - |
dc.contributor.author | Oh, Dong Joo | - |
dc.date.accessioned | 2021-09-02T14:05:25Z | - |
dc.date.available | 2021-09-02T14:05:25Z | - |
dc.date.created | 2021-06-16 | - |
dc.date.issued | 2018-03 | - |
dc.identifier.issn | 1875-2136 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/76863 | - |
dc.description.abstract | Background. - Long-term clinical outcome data according to severity of coronary artery spasm (CAS) as assessed by an intracoronary acetylcholine provocation test are limited in series of Asian patients. Aim. - To investigate 5-year clinical outcomes in patients with CAS according to CAS severity. Methods. - In total, 5873 consecutive patients with insignificant coronary artery disease (< 70% fixed stenosis) who underwent an acetylcholine provocation test were enrolled and divided into four groups according to CAS severity during the acetylcholine provocation test: negative, borderline positive, moderately positive and severely positive. CAS severity was assessed by quantitative coronary angiography. We investigated 5-year clinical outcomes according to CAS severity. Results. - Over a follow-up period of up to 5 years, before adjustment, the severely-positive CAS group showed a significantly higher incidence of major adverse cardiac events (MACE; composite of death, myocardial infarction and de novo revascularization) (hazard ratio [HR]: 1.834, 95% confidence interval [CI]: 1.047-3.211; P=0.033), total death (HR: 3.124, 95% CI: 1.047-9.322; P=0.041), myocardial infarction (HR: 3.190, 95% CI: 1.069-9.519; P=0.037) and recurrent angina (HR: 1.762, 95% CI: 1.363-2.278; P< 0.001) compared with the negative group. However, after adjustment for baseline confounders, only the incidence of recurrent angina (HR: 1.323, 95% CI: 1.014-1.726; P= 0.039) was significantly higher in the severely-positive CAS group compared with the negative group. Conclusions. - The severity of CAS in the positive group was not associated with an increased incidence of MACE after adjustment for covariates compared with the negative group, but the severely -positive CAS group was associated with a higher incidence of recurrent angina compared with the negative group. (C) 2017 Elsevier Masson SAS. All rights reserved. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER MASSON, CORPORATION OFFICE | - |
dc.subject | LONG-TERM PROGNOSIS | - |
dc.subject | VASOSPASTIC ANGINA | - |
dc.subject | VARIANT ANGINA | - |
dc.subject | FOLLOW-UP | - |
dc.subject | PATHOGENESIS | - |
dc.subject | DIAGNOSIS | - |
dc.subject | STENOSIS | - |
dc.subject | JAPANESE | - |
dc.subject | IMPACT | - |
dc.subject | SAFETY | - |
dc.title | Five-year major clinical outcomes according to severity of coronary artery spasm as assessed by intracoronary acetylcholine provocation test | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Rha, Seung-Woon | - |
dc.contributor.affiliatedAuthor | Na, Jin Oh | - |
dc.contributor.affiliatedAuthor | Choi, Cheol Ung | - |
dc.contributor.affiliatedAuthor | Lim, Hong Euy | - |
dc.contributor.affiliatedAuthor | Kim, Eung Ju | - |
dc.contributor.affiliatedAuthor | Park, Chang Gyu | - |
dc.contributor.affiliatedAuthor | Seo, Hong Seog | - |
dc.contributor.affiliatedAuthor | Oh, Dong Joo | - |
dc.identifier.doi | 10.1016/j.acvd.2017.05.008 | - |
dc.identifier.scopusid | 2-s2.0-85030839906 | - |
dc.identifier.wosid | 000433267400002 | - |
dc.identifier.bibliographicCitation | ARCHIVES OF CARDIOVASCULAR DISEASES, v.111, no.3, pp.144 - 154 | - |
dc.relation.isPartOf | ARCHIVES OF CARDIOVASCULAR DISEASES | - |
dc.citation.title | ARCHIVES OF CARDIOVASCULAR DISEASES | - |
dc.citation.volume | 111 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 144 | - |
dc.citation.endPage | 154 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Cardiovascular System & Cardiology | - |
dc.relation.journalWebOfScienceCategory | Cardiac & Cardiovascular Systems | - |
dc.subject.keywordPlus | LONG-TERM PROGNOSIS | - |
dc.subject.keywordPlus | VASOSPASTIC ANGINA | - |
dc.subject.keywordPlus | VARIANT ANGINA | - |
dc.subject.keywordPlus | FOLLOW-UP | - |
dc.subject.keywordPlus | PATHOGENESIS | - |
dc.subject.keywordPlus | DIAGNOSIS | - |
dc.subject.keywordPlus | STENOSIS | - |
dc.subject.keywordPlus | JAPANESE | - |
dc.subject.keywordPlus | IMPACT | - |
dc.subject.keywordPlus | SAFETY | - |
dc.subject.keywordAuthor | Coronary artery spasm | - |
dc.subject.keywordAuthor | Acetylcholine | - |
dc.subject.keywordAuthor | Clinical outcomes | - |
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