An efficient synthetic protocol for amide derivatives of Boc-2-aminoisobutyrate
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Jo, Minmi | - |
dc.contributor.author | Won, Sun-Woo | - |
dc.contributor.author | Lee, Dong Guk | - |
dc.contributor.author | Jung, Jae-Kyung | - |
dc.contributor.author | Kim, Sunhong | - |
dc.contributor.author | Kwak, Young-Shin | - |
dc.date.accessioned | 2021-09-02T14:40:25Z | - |
dc.date.available | 2021-09-02T14:40:25Z | - |
dc.date.created | 2021-06-16 | - |
dc.date.issued | 2018-03 | - |
dc.identifier.issn | 0253-6269 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/77210 | - |
dc.description.abstract | Aminoisobutyric acid (AIB) is an important building block widely incorporated by medicinal chemists in molecular design. Owing to the steric challenge, elaborating AIB's carboxylic acid using conventional amidation protocols is often problematic. We discovered that an amidation protocol utilizing methyl Boc-aminoisobutyrate and magnesium amidates of various reactivities produces the corresponding amide derivatives in good to excellent yields. [GRAPHICS] . | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | PHARMACEUTICAL SOC KOREA | - |
dc.subject | AMINO-ACIDS | - |
dc.title | An efficient synthetic protocol for amide derivatives of Boc-2-aminoisobutyrate | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kwak, Young-Shin | - |
dc.identifier.doi | 10.1007/s12272-018-1009-3 | - |
dc.identifier.scopusid | 2-s2.0-85042437907 | - |
dc.identifier.wosid | 000427905600002 | - |
dc.identifier.bibliographicCitation | ARCHIVES OF PHARMACAL RESEARCH, v.41, no.3, pp.259 - 264 | - |
dc.relation.isPartOf | ARCHIVES OF PHARMACAL RESEARCH | - |
dc.citation.title | ARCHIVES OF PHARMACAL RESEARCH | - |
dc.citation.volume | 41 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 259 | - |
dc.citation.endPage | 264 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART002325695 | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Medicinal | - |
dc.relation.journalWebOfScienceCategory | Pharmacology & Pharmacy | - |
dc.subject.keywordPlus | AMINO-ACIDS | - |
dc.subject.keywordAuthor | Transmidation | - |
dc.subject.keywordAuthor | t-butylmagnesiumchloride | - |
dc.subject.keywordAuthor | Steric challenge | - |
dc.subject.keywordAuthor | Methyl Boc-aminoisobutyrate | - |
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