Effects of exercise on sexual function and central mechanism in the streptozotocin-induced diabetic rats
DC Field | Value | Language |
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dc.contributor.author | Lee, Jae-Min | - |
dc.contributor.author | Kim, Tae-Woon | - |
dc.contributor.author | Park, Hye-Sang | - |
dc.contributor.author | Park, Sang-Seo | - |
dc.contributor.author | Shin, Mal-Soon | - |
dc.contributor.author | Sung, Yun-Hee | - |
dc.contributor.author | Seo, Tae-Beom | - |
dc.contributor.author | Kim, Young-Pyo | - |
dc.date.accessioned | 2021-09-02T15:13:58Z | - |
dc.date.available | 2021-09-02T15:13:58Z | - |
dc.date.created | 2021-06-16 | - |
dc.date.issued | 2018-02 | - |
dc.identifier.issn | 2288-176X | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/77472 | - |
dc.description.abstract | Diabetes mellitus is associated with the impairment of sexual function including desire and orgasmic dysfunction. Sexual dysfunction in the diabetes mellitus is due to a selective defect of the nitric oxide synthase (NOS) within paraventricular nucleus (PVN). c-Fos is an immediate early gene and c-Fos expression represents neuronal activity in response to various stimuli. In the present study, we investigated the effects of treadmill exercise on sexual behaviors and the expressions of NOS and c-Fos in the PVN were evaluated using streptozotocin (STZ)-induced diabetic rats. Diabetes mellitus was induced by intraperitoneal injection of STZ. The rats in the treadmill exercise groups were made to run on a treadmill for 30 min once a day during 4 weeks. Male sexual behaviors were evaluated by recording the number of mounting, intromission, and ejaculation frequency. The present results revealed that treadmill exercise ameliorated sexual dysfunction in the STZ-induced diabetic rats. Treadmill exercise restored the contents of NOS and c-Fos in the PVN. The improving effect of treadmill exercise on sexual function can be considered as the neuronal activating effect of exercise through increasing expressions of NO and c-Fos. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | KOREAN SOC EXERCISE REHABILITATION | - |
dc.subject | NITRIC-OXIDE SYNTHASE | - |
dc.subject | C-FOS EXPRESSION | - |
dc.subject | ERECTILE DYSFUNCTION | - |
dc.subject | TREADMILL EXERCISE | - |
dc.subject | PHYSICAL-ACTIVITY | - |
dc.subject | INDUCED INCREASE | - |
dc.subject | HIPPOCAMPUS | - |
dc.subject | MELLITUS | - |
dc.subject | MEMORY | - |
dc.subject | MEN | - |
dc.title | Effects of exercise on sexual function and central mechanism in the streptozotocin-induced diabetic rats | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Shin, Mal-Soon | - |
dc.identifier.doi | 10.12965/jer.1836072.036 | - |
dc.identifier.scopusid | 2-s2.0-85043721000 | - |
dc.identifier.wosid | 000429087100004 | - |
dc.identifier.bibliographicCitation | JOURNAL OF EXERCISE REHABILITATION, v.14, no.1, pp.10 - 15 | - |
dc.relation.isPartOf | JOURNAL OF EXERCISE REHABILITATION | - |
dc.citation.title | JOURNAL OF EXERCISE REHABILITATION | - |
dc.citation.volume | 14 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 10 | - |
dc.citation.endPage | 15 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART002320097 | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Rehabilitation | - |
dc.relation.journalWebOfScienceCategory | Rehabilitation | - |
dc.subject.keywordPlus | NITRIC-OXIDE SYNTHASE | - |
dc.subject.keywordPlus | C-FOS EXPRESSION | - |
dc.subject.keywordPlus | ERECTILE DYSFUNCTION | - |
dc.subject.keywordPlus | TREADMILL EXERCISE | - |
dc.subject.keywordPlus | PHYSICAL-ACTIVITY | - |
dc.subject.keywordPlus | INDUCED INCREASE | - |
dc.subject.keywordPlus | HIPPOCAMPUS | - |
dc.subject.keywordPlus | MELLITUS | - |
dc.subject.keywordPlus | MEMORY | - |
dc.subject.keywordPlus | MEN | - |
dc.subject.keywordAuthor | Diabetes mellitus | - |
dc.subject.keywordAuthor | Treadmill exercise | - |
dc.subject.keywordAuthor | Sexual dysfunction | - |
dc.subject.keywordAuthor | Nitric oxide | - |
dc.subject.keywordAuthor | c-Fos | - |
dc.subject.keywordAuthor | Paraventricular nucleus | - |
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