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Preeclampsia Increases the Incidence of Postpartum Cerebrovascular Disease in Korean Population

Authors
Park, YejinCho, Geum JoonKim, Log YoungLee, Tae-SeonOh, Min-JeongKim, Young-Han
Issue Date
2월-2018
Publisher
KOREAN ACAD MEDICAL SCIENCES
Keywords
Cerebrovascular Disease; Pregnancy; Postpartum Period; Preeclampsia; Insurance Claim Reporting; Korea
Citation
JOURNAL OF KOREAN MEDICAL SCIENCE, v.33, no.6
Indexed
SCIE
SCOPUS
KCI
Journal Title
JOURNAL OF KOREAN MEDICAL SCIENCE
Volume
33
Number
6
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/77802
DOI
10.3346/jkms.2018.33.e35
ISSN
1011-8934
Abstract
Background: Multiple studies have been reported regarding preeclampsia as a possible risk factor of cerebrovascular disease (CVD). However, the correlation of preeclampsia and CVD, whether it is a cause-effect relationship or they are sharing common predisposing condition, is not well understood. Therefore, the aim of this study was to investigate the association between the preeclampsia during pregnancy and development of postpartum CVD. Methods: A total of 1,384,550 Korean women who had a delivery between January 1, 2010 and December 31, 2012, were enrolled. Women with the risk of CVD within 1 year prior to pregnancy were excluded based on the Charlson comorbidity index. Primary endpoint was the event of CVD within a year from delivery. After exclusion, 1,075,061 women were analyzed. Results: During the follow-up of 1 year postpartum, there were 25,577 preeclampsia out of 1,072,041 women without postpartum CVD (2.39%), and 121 of 3,020 women with postpartum CVD had preeclampsia before delivery (4.01%). In multivariate logistic regression analysis, women who had preeclampsia during pregnancy showed a higher risk for postpartum CVD (odds ratio, 1.64; 95% confidence interval, 1.37-1.98). Conclusion: The incidence of CVD after delivery was higher in women who had preeclampsia during pregnancy.
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의과대학 (의학과)
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