Exposure to lead and mercury through breastfeeding during the first month of life: A CHECK cohort study
DC Field | Value | Language |
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dc.contributor.author | Park, Yelim | - |
dc.contributor.author | Lee, Aram | - |
dc.contributor.author | Choi, Kyungho | - |
dc.contributor.author | Kim, Hai-Joong | - |
dc.contributor.author | Lee, Jeong Jae | - |
dc.contributor.author | Choi, Gyuyeon | - |
dc.contributor.author | Kim, Sungjoo | - |
dc.contributor.author | Kim, Su Young | - |
dc.contributor.author | Cho, Geum Joon | - |
dc.contributor.author | Suh, Eunsook | - |
dc.contributor.author | Kim, Sung Koo | - |
dc.contributor.author | Eun, So-Hee | - |
dc.contributor.author | Eom, Soyong | - |
dc.contributor.author | Kim, Seunghyo | - |
dc.contributor.author | Kim, Gun-Ha | - |
dc.contributor.author | Moon, Hyo-Bang | - |
dc.contributor.author | Kim, Sungkyoon | - |
dc.contributor.author | Choi, Sooran | - |
dc.contributor.author | Kim, Young Don | - |
dc.contributor.author | Kim, Jinho | - |
dc.contributor.author | Park, Jeongim | - |
dc.date.accessioned | 2021-09-02T16:10:31Z | - |
dc.date.available | 2021-09-02T16:10:31Z | - |
dc.date.created | 2021-06-16 | - |
dc.date.issued | 2018-01-15 | - |
dc.identifier.issn | 0048-9697 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/77977 | - |
dc.description.abstract | Mercury and lead are naturally occurring toxicants and are responsible for various health issues including neuro-behavioral and developmental disorders. Because of crucial synchronized developmental processes occurring at the early stage of life, infancy and childhood are considered as among the most susceptible windows to the exposure to these metals. Breastmilk is often the only source of nutrition during the first months of life. As breastmilk can be contaminated with these metals, breastfeeding may serve as a significant route of heavy metal exposure among infants. In order to understand current levels of exposure to mercury and lead through breastfeeding, and their associated risks, a total of 157 lactating mothers were recruited from Children's Health and Environmental Chemicals of Korea (CHECK) cohort, and breastmilk samples were collected at 15 and 30 days after delivery (n = 207). Mercury was detected from 100% of breastmilk with a median concentration of 0.59 mu g/L, and lead was detected in 77% of the samples with a median at 4.71 mu g/L. Higher concentrations of lead were found in the 30-day breastmilk than in the 15-day. Up to 45% of the breastmilk samples exceeded the normal range of the breastmilk lead suggested by WHO. Based on Monte Carlo simulation, about 71% of 15 days old infants and 56% of 30 days old infants were estimated at risk due to lead exposure through breastfeeding. Considering vulnerability of infants and well-known neurological toxicity of these metals, further studies to identify major exposure sources that contribute the lead concentration in breastmilk and health implication of early life stage exposure to lead among the breastfed infants are warranted. (C) 2017 Elsevier B.V. All rights reserved. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER | - |
dc.subject | ENVIRONMENTAL-HEALTH SURVEY | - |
dc.subject | HUMAN-MILK | - |
dc.subject | FISH CONSUMPTION | - |
dc.subject | BLOOD LEAD | - |
dc.subject | CADMIUM LEVELS | - |
dc.subject | SUBURBAN AREAS | - |
dc.subject | HEAVY-METALS | - |
dc.subject | CHILDREN | - |
dc.subject | ASSOCIATION | - |
dc.subject | INFANTS | - |
dc.title | Exposure to lead and mercury through breastfeeding during the first month of life: A CHECK cohort study | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Hai-Joong | - |
dc.contributor.affiliatedAuthor | Cho, Geum Joon | - |
dc.contributor.affiliatedAuthor | Eun, So-Hee | - |
dc.contributor.affiliatedAuthor | Kim, Gun-Ha | - |
dc.identifier.doi | 10.1016/j.scitotenv.2017.08.079 | - |
dc.identifier.scopusid | 2-s2.0-85028701420 | - |
dc.identifier.wosid | 000413313700086 | - |
dc.identifier.bibliographicCitation | SCIENCE OF THE TOTAL ENVIRONMENT, v.612, pp.876 - 883 | - |
dc.relation.isPartOf | SCIENCE OF THE TOTAL ENVIRONMENT | - |
dc.citation.title | SCIENCE OF THE TOTAL ENVIRONMENT | - |
dc.citation.volume | 612 | - |
dc.citation.startPage | 876 | - |
dc.citation.endPage | 883 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Environmental Sciences & Ecology | - |
dc.relation.journalWebOfScienceCategory | Environmental Sciences | - |
dc.subject.keywordPlus | ENVIRONMENTAL-HEALTH SURVEY | - |
dc.subject.keywordPlus | HUMAN-MILK | - |
dc.subject.keywordPlus | FISH CONSUMPTION | - |
dc.subject.keywordPlus | BLOOD LEAD | - |
dc.subject.keywordPlus | CADMIUM LEVELS | - |
dc.subject.keywordPlus | SUBURBAN AREAS | - |
dc.subject.keywordPlus | HEAVY-METALS | - |
dc.subject.keywordPlus | CHILDREN | - |
dc.subject.keywordPlus | ASSOCIATION | - |
dc.subject.keywordPlus | INFANTS | - |
dc.subject.keywordAuthor | Mercury | - |
dc.subject.keywordAuthor | Lead | - |
dc.subject.keywordAuthor | Breastmilk | - |
dc.subject.keywordAuthor | Daily intake | - |
dc.subject.keywordAuthor | Probabilistic risk estimation | - |
dc.subject.keywordAuthor | CHECK | - |
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