소아 뇌전증 환자에서 발열이 동반된 경련을 하는 것과 저 이온화 마그네슘 혈증과의 관련성
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 서선희 | - |
dc.contributor.author | 김경주 | - |
dc.contributor.author | 변정혜 | - |
dc.contributor.author | 은소희 | - |
dc.contributor.author | 은백린 | - |
dc.contributor.author | 김건하 | - |
dc.date.accessioned | 2021-09-02T17:24:35Z | - |
dc.date.available | 2021-09-02T17:24:35Z | - |
dc.date.created | 2021-06-17 | - |
dc.date.issued | 2018 | - |
dc.identifier.issn | 1226-6884 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/78632 | - |
dc.description.abstract | Purpose: Several studies have shown that magnesium plays an important role in modulating N-methyl-D-aspartate (NMDA)-related seizures by blocking NMDA ion channel receptors. Clinicians usually measure total serum magnesium levels instead of biologically active ionized magnesium levels. We compared the serum ionized magnesium (iMg2+) level between epileptic children with and without a history of fever-triggered seizure (FTS). Methods: All epileptic children who visited the outpatient clinic or pediatric emergency department at Korea University Guro Hospital between January 2015 and July 2017 were included. Only epileptic children aged 1-8 years who were newly diagnosed within 2 years were included. Results: There were 12 children with FTS and 16 without FTS. Median serum iMg2+ level was 0.93 (0.85-1.14, quartile) mEq/L. Serum iMg2+ level was significantly lower in epileptic children with FTS (0.86 mEq/L) compared to those without FTS (1.10 mEq/L) (P=0.005). No difference was noted in clinical variables between the two groups. Lower serum iMg2+ level significantly increased the risk of having FTS in epileptic children based on multivariable logistic regression analysis (odds ratio [OR]=0.028). Conclusion: Serum iMg2+ level was significantly lower in epileptic children with FTS than in those without FTS. Measurement of biologically active serum iMg2+ level could be considered in epileptic children with recurrent FTS. A large-scale prospective study is warranted. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | 대한소아신경학회 | - |
dc.title | 소아 뇌전증 환자에서 발열이 동반된 경련을 하는 것과 저 이온화 마그네슘 혈증과의 관련성 | - |
dc.title.alternative | Association of Low Serum Ionized Magnesium Level with Fever-Triggered Seizures in Epileptic Children | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | 변정혜 | - |
dc.identifier.bibliographicCitation | 대한소아신경학회지, v.26, no.4, pp.205 - 209 | - |
dc.relation.isPartOf | 대한소아신경학회지 | - |
dc.citation.title | 대한소아신경학회지 | - |
dc.citation.volume | 26 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 205 | - |
dc.citation.endPage | 209 | - |
dc.type.rims | ART | - |
dc.identifier.kciid | ART002416740 | - |
dc.description.journalClass | 2 | - |
dc.description.journalRegisteredClass | kci | - |
dc.description.journalRegisteredClass | other | - |
dc.subject.keywordAuthor | Epilepsy | - |
dc.subject.keywordAuthor | Magnesium | - |
dc.subject.keywordAuthor | Febrile convulsion | - |
dc.subject.keywordAuthor | Child | - |
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