Schweinfurthins A-Q: isolation, synthesis, and biochemical properties
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Harmalkar, Dipesh S. | - |
dc.contributor.author | Mali, Jyotirling R. | - |
dc.contributor.author | Sivaraman, Aneesh | - |
dc.contributor.author | Choi, Yongseok | - |
dc.contributor.author | Lee, Kyeong | - |
dc.date.accessioned | 2021-09-02T21:13:51Z | - |
dc.date.available | 2021-09-02T21:13:51Z | - |
dc.date.created | 2021-06-16 | - |
dc.date.issued | 2018 | - |
dc.identifier.issn | 2046-2069 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/80937 | - |
dc.description.abstract | Stilbene analogues have shown remarkable structural diversity constituting simple or tangled structures, which have attracted the synthetic as well as the medicinal chemistry communities. Schweinfurthins are a family of prenylated/geranylated/farnesylated stilbenes that are isolated from an African plant belonging to the Macaranga species. These compounds have displayed potency towards central nervous system, renal and breast cancer cell lines. Specifically, these compounds have been found to be potent and selective inhibitors of cell growth in the National Cancer Institute's 60 cell-line screen. In this review article, we described the isolation, synthesis, and biochemical properties of schweinfurthins. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | ROYAL SOC CHEMISTRY | - |
dc.subject | MACARANGA-SCHWEINFURTHII | - |
dc.subject | ANTIOXIDANT ACTIVITY | - |
dc.subject | DRUG DISCOVERY | - |
dc.subject | ASYMMETRIC EPOXIDATION | - |
dc.subject | ARUNDINA-GRAMINIFOLIA | - |
dc.subject | PRENYLATED STILBENES | - |
dc.subject | OLEFIN CYCLIZATION | - |
dc.subject | GERANYL STILBENES | - |
dc.subject | NATURAL-PRODUCTS | - |
dc.subject | BREAST-CANCER | - |
dc.title | Schweinfurthins A-Q: isolation, synthesis, and biochemical properties | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Choi, Yongseok | - |
dc.identifier.doi | 10.1039/c8ra02872a | - |
dc.identifier.scopusid | 2-s2.0-85048809516 | - |
dc.identifier.wosid | 000435576500014 | - |
dc.identifier.bibliographicCitation | RSC ADVANCES, v.8, no.38, pp.21191 - 21209 | - |
dc.relation.isPartOf | RSC ADVANCES | - |
dc.citation.title | RSC ADVANCES | - |
dc.citation.volume | 8 | - |
dc.citation.number | 38 | - |
dc.citation.startPage | 21191 | - |
dc.citation.endPage | 21209 | - |
dc.type.rims | ART | - |
dc.type.docType | Review | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
dc.subject.keywordPlus | MACARANGA-SCHWEINFURTHII | - |
dc.subject.keywordPlus | ANTIOXIDANT ACTIVITY | - |
dc.subject.keywordPlus | DRUG DISCOVERY | - |
dc.subject.keywordPlus | ASYMMETRIC EPOXIDATION | - |
dc.subject.keywordPlus | ARUNDINA-GRAMINIFOLIA | - |
dc.subject.keywordPlus | PRENYLATED STILBENES | - |
dc.subject.keywordPlus | OLEFIN CYCLIZATION | - |
dc.subject.keywordPlus | GERANYL STILBENES | - |
dc.subject.keywordPlus | NATURAL-PRODUCTS | - |
dc.subject.keywordPlus | BREAST-CANCER | - |
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