BLT2, a leukotriene B-4 receptor 2, as a novel prognostic biomarker of triple-negative breast cancer
DC Field | Value | Language |
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dc.contributor.author | Park, Jaein | - |
dc.contributor.author | Jang, Jae-Hyun | - |
dc.contributor.author | Park, Geun-Soo | - |
dc.contributor.author | Chung, Yunro | - |
dc.contributor.author | You, Hye Jin | - |
dc.contributor.author | Kim, Jae-Hong | - |
dc.date.accessioned | 2021-09-02T21:22:45Z | - |
dc.date.available | 2021-09-02T21:22:45Z | - |
dc.date.created | 2021-06-16 | - |
dc.date.issued | 2018 | - |
dc.identifier.issn | 1976-6696 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/81011 | - |
dc.description.abstract | Triple-negative breast cancer (TNBC) is considered to be a notorious type of cancer due to its aggressive metastatic potential and poor prognosis. Recent evidence suggests that BLT2, a low-affinity LTB4 receptor is critically associated with the phenotypes of TNBC cells, including invasion, metastasis, and survival. Furthermore, in a group of 545 breast cancer patients with metastasis, we observed that the high-BLT2 subgroup had a lower disease-free-survival rate than the low-BLT2 subgroup. Thus, we theorized that anti-BLT2 strategies could facilitate the development of new therapies used for TNBC. This review focuses on recent discoveries regarding BLT2 and its roles in as a novel prognostic biomarker in TNBC. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | KOREAN SOCIETY BIOCHEMISTRY & MOLECULAR BIOLOGY | - |
dc.subject | MONOCYTES | - |
dc.subject | ADHESION | - |
dc.subject | CELLS | - |
dc.subject | EXPRESSION | - |
dc.subject | PHENOTYPE | - |
dc.subject | CYTOKINES | - |
dc.subject | SURVIVAL | - |
dc.subject | INVASION | - |
dc.subject | GROWTH | - |
dc.subject | IL-6 | - |
dc.title | BLT2, a leukotriene B-4 receptor 2, as a novel prognostic biomarker of triple-negative breast cancer | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Jae-Hong | - |
dc.identifier.doi | 10.5483/BMBRep.2018.51.8.127 | - |
dc.identifier.scopusid | 2-s2.0-85055070963 | - |
dc.identifier.wosid | 000452141700003 | - |
dc.identifier.bibliographicCitation | BMB REPORTS, v.51, no.8, pp.373 - 377 | - |
dc.relation.isPartOf | BMB REPORTS | - |
dc.citation.title | BMB REPORTS | - |
dc.citation.volume | 51 | - |
dc.citation.number | 8 | - |
dc.citation.startPage | 373 | - |
dc.citation.endPage | 377 | - |
dc.type.rims | ART | - |
dc.type.docType | Review | - |
dc.identifier.kciid | ART002377200 | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
dc.subject.keywordPlus | MONOCYTES | - |
dc.subject.keywordPlus | ADHESION | - |
dc.subject.keywordPlus | CELLS | - |
dc.subject.keywordPlus | EXPRESSION | - |
dc.subject.keywordPlus | PHENOTYPE | - |
dc.subject.keywordPlus | CYTOKINES | - |
dc.subject.keywordPlus | SURVIVAL | - |
dc.subject.keywordPlus | INVASION | - |
dc.subject.keywordPlus | GROWTH | - |
dc.subject.keywordPlus | IL-6 | - |
dc.subject.keywordAuthor | BLT2 | - |
dc.subject.keywordAuthor | Leukotriene B4 receptor-2 | - |
dc.subject.keywordAuthor | TNBC | - |
dc.subject.keywordAuthor | Triple-negative breast cancer | - |
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