Five-year major clinical outcomes between first-generation and second-generation drug-eluting stents in acute myocardial infarction patients underwent percutaneous coronary intervention
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Yong Hoon | - |
dc.contributor.author | Her, Ae-Young | - |
dc.contributor.author | Rha, Seung-Woon | - |
dc.contributor.author | Choi, Byoung Geol | - |
dc.contributor.author | Choi, Se Yeon | - |
dc.contributor.author | Byun, Jae Kyeong | - |
dc.contributor.author | Baek, Ju Yeol | - |
dc.contributor.author | Choi, Woong Gil | - |
dc.contributor.author | Kang, Tae Soo | - |
dc.contributor.author | Ahn, Ji Hoon | - |
dc.contributor.author | Park, Sang-Ho | - |
dc.contributor.author | Mashaly, Ahmed | - |
dc.contributor.author | Na, Jin Oh | - |
dc.contributor.author | Choi, Cheol Ung | - |
dc.contributor.author | Lim, Hong Euy | - |
dc.contributor.author | Kim, Eung Ju | - |
dc.contributor.author | Park, Chang Gyu | - |
dc.contributor.author | Seo, Hong Seog | - |
dc.contributor.author | Oh, Dong Joo | - |
dc.date.accessioned | 2021-09-02T21:32:04Z | - |
dc.date.available | 2021-09-02T21:32:04Z | - |
dc.date.created | 2021-06-16 | - |
dc.date.issued | 2018 | - |
dc.identifier.issn | 1671-5411 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/81082 | - |
dc.description.abstract | Background There were limited data comparing the major clinical outcomes between first-generation (1G)-drug eluting stents (DES) and second-generation (2G)-DES in patients with acute myocardial infarction (AMI) after percutaneous coronary intervention (PCI) during very long follow-up periods. We thought to investigate the comparative efficacy and safety of 2G-DES compared with 1G-DES in AMI patients during 5-year follow-up periods. Method A total of 1016 eligible AMI patients who underwent PCI with 1G-DES [paclitaxel-, sirolimus-, 1G-zotarolimus-eluting stent (endeavor (R) or endeavor sprint (R)), n = 554] or 2G-DES [2G-zotarolimus (endeavor resolute (R))- or everolimus-eluting stent, n = 462] were enrolled. The primary endpoint was the occurrence of major adverse cardiac events (MACE) defined as total death, non-fatal myocardial infarction (MI), target lesion revascularization (TLR), target vessel revascularization (TVR), non-target vessel revascularization (Non-TVR) and the secondary endpoint was stent thrombosis (ST) at 5 years. Results Two propensity score-matched (PSM) groups (232 pairs, n = 464, C-statistic = 0.802) were generated. During the 5-year follow-up period, the cumulative incidence of TLR [hazard ratio (HR): 3.133; 95% confidence interval (CI): 1.539-6.376; P = 0.002], TVR (HR: 3.144; 95% CI: 1.596-6.192; P = 0.001) and total revascularization rate (HR: 1.874; 95% CI: 1.086-3.140; P = 0.023) were significantly higher in 1G-DES compared with 2G-DES after PSM. However, the incidence of total death, non-fatal MI and ST were similar between the two groups. Conclusion In this single-center and all-comers registry, 2G-DES's superiorities for TLR, TVR and total revascularization in AMI patients suggested during 5-year clinical follow-up periods. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | SCIENCE PRESS | - |
dc.subject | RANDOMIZED-TRIALS | - |
dc.subject | FOLLOW-UP | - |
dc.subject | EVEROLIMUS | - |
dc.subject | SIROLIMUS | - |
dc.subject | METAANALYSIS | - |
dc.subject | RESOLUTE | - |
dc.subject | IMPACT | - |
dc.subject | TERM | - |
dc.title | Five-year major clinical outcomes between first-generation and second-generation drug-eluting stents in acute myocardial infarction patients underwent percutaneous coronary intervention | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Rha, Seung-Woon | - |
dc.contributor.affiliatedAuthor | Na, Jin Oh | - |
dc.contributor.affiliatedAuthor | Choi, Cheol Ung | - |
dc.contributor.affiliatedAuthor | Lim, Hong Euy | - |
dc.contributor.affiliatedAuthor | Kim, Eung Ju | - |
dc.contributor.affiliatedAuthor | Park, Chang Gyu | - |
dc.contributor.affiliatedAuthor | Seo, Hong Seog | - |
dc.identifier.doi | 10.11909/j.issn.1671-5411.2018.08.006 | - |
dc.identifier.scopusid | 2-s2.0-85054556730 | - |
dc.identifier.wosid | 000456682800002 | - |
dc.identifier.bibliographicCitation | JOURNAL OF GERIATRIC CARDIOLOGY, v.15, no.8, pp.523 - 533 | - |
dc.relation.isPartOf | JOURNAL OF GERIATRIC CARDIOLOGY | - |
dc.citation.title | JOURNAL OF GERIATRIC CARDIOLOGY | - |
dc.citation.volume | 15 | - |
dc.citation.number | 8 | - |
dc.citation.startPage | 523 | - |
dc.citation.endPage | 533 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Cardiovascular System & Cardiology | - |
dc.relation.journalResearchArea | Geriatrics & Gerontology | - |
dc.relation.journalWebOfScienceCategory | Cardiac & Cardiovascular Systems | - |
dc.relation.journalWebOfScienceCategory | Geriatrics & Gerontology | - |
dc.subject.keywordPlus | RANDOMIZED-TRIALS | - |
dc.subject.keywordPlus | FOLLOW-UP | - |
dc.subject.keywordPlus | EVEROLIMUS | - |
dc.subject.keywordPlus | SIROLIMUS | - |
dc.subject.keywordPlus | METAANALYSIS | - |
dc.subject.keywordPlus | RESOLUTE | - |
dc.subject.keywordPlus | IMPACT | - |
dc.subject.keywordPlus | TERM | - |
dc.subject.keywordAuthor | Acute myocardial infarction | - |
dc.subject.keywordAuthor | Clinical outcomes | - |
dc.subject.keywordAuthor | Drug-eluting stent | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
145 Anam-ro, Seongbuk-gu, Seoul, 02841, Korea+82-2-3290-2963
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.