Electrode Impedance Fluctuations as a Biomarker for Inner Ear Pathology After Cochlear Implantation
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Choi, June | - |
dc.contributor.author | Payne, Matthew R. | - |
dc.contributor.author | Campbell, Luke J. | - |
dc.contributor.author | Bester, Christo W. | - |
dc.contributor.author | Newbold, Carrie | - |
dc.contributor.author | Eastwood, Hayden | - |
dc.contributor.author | O'Leary, Stephen J. | - |
dc.date.accessioned | 2021-09-02T22:13:18Z | - |
dc.date.available | 2021-09-02T22:13:18Z | - |
dc.date.created | 2021-06-16 | - |
dc.date.issued | 2017-12 | - |
dc.identifier.issn | 1531-7129 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/81275 | - |
dc.description.abstract | Objectives/Hypothesis: Cochlear implant surgery now aims to preserve residual low frequency hearing. The current research explores whether fluctuations in the electrical impedance of cochlear implant electrodes may act as a biomarker for pathological changes that lead to the delayed loss of residual hearing. Study Design: Secondary analysis of a double-blinded randomized trial, where methylprednisolone was administered intravenously before cochlear implantation with a view to preserving residual hearing. Methods: Seventy-four patients with residual hearing after cochlear implant surgery were investigated for an impedance "spike," defined as a median rise of >= 4kV across all electrodes from the baseline measurements. Spikes were related to objective and subjective hearing loss, dizziness, and tinnitus. Results: An impedance spike occurred in 14% (10/74) of enrolled patients. Three months after surgery, five patients exhibited spikes and three of these patients had a total loss of their residual hearing. 4.3% of the 69 patients without spikes lost residual hearing. At 1 year, 9 of 10 patients who exhibited spikes had lost all their residual hearing. 8.1% of the 37 patients who did not experience a spike lost their residual hearing. Seventy percent of patients exhibiting a spike also experienced vertigo. The administration of steroids at the time of surgery did not influence the occurrence of spikes. Conclusion: Our results suggest that there is a relationship between a spike and the loss of residual hearing. It seems that rises in impedance can reflect pathology within the inner ear and predict the future loss of residual hearing. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | LIPPINCOTT WILLIAMS & WILKINS | - |
dc.subject | MENIERES-DISEASE | - |
dc.subject | ENDOLYMPHATIC HYDROPS | - |
dc.subject | HEARING PRESERVATION | - |
dc.subject | HISTOPATHOLOGY | - |
dc.subject | STIMULATION | - |
dc.title | Electrode Impedance Fluctuations as a Biomarker for Inner Ear Pathology After Cochlear Implantation | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Choi, June | - |
dc.identifier.doi | 10.1097/MAO.0000000000001589 | - |
dc.identifier.scopusid | 2-s2.0-85033787012 | - |
dc.identifier.wosid | 000425284200039 | - |
dc.identifier.bibliographicCitation | OTOLOGY & NEUROTOLOGY, v.38, no.10, pp.1433 - 1439 | - |
dc.relation.isPartOf | OTOLOGY & NEUROTOLOGY | - |
dc.citation.title | OTOLOGY & NEUROTOLOGY | - |
dc.citation.volume | 38 | - |
dc.citation.number | 10 | - |
dc.citation.startPage | 1433 | - |
dc.citation.endPage | 1439 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Neurosciences & Neurology | - |
dc.relation.journalResearchArea | Otorhinolaryngology | - |
dc.relation.journalWebOfScienceCategory | Clinical Neurology | - |
dc.relation.journalWebOfScienceCategory | Otorhinolaryngology | - |
dc.subject.keywordPlus | MENIERES-DISEASE | - |
dc.subject.keywordPlus | ENDOLYMPHATIC HYDROPS | - |
dc.subject.keywordPlus | HEARING PRESERVATION | - |
dc.subject.keywordPlus | HISTOPATHOLOGY | - |
dc.subject.keywordPlus | STIMULATION | - |
dc.subject.keywordAuthor | Cochlear implant | - |
dc.subject.keywordAuthor | Impedance | - |
dc.subject.keywordAuthor | Residual hearing | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(02841) 서울특별시 성북구 안암로 14502-3290-1114
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.