Production of 5-aminovaleric acid in recombinant Corynebacterium glutamicum strains from a Miscanthus hydrolysate solution prepared by a newly developed Miscanthus hydrolysis process
DC Field | Value | Language |
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dc.contributor.author | Joo, Jeong Chan | - |
dc.contributor.author | Oh, Young Hoon | - |
dc.contributor.author | Yu, Ju Hyun | - |
dc.contributor.author | Hyun, Sung Min | - |
dc.contributor.author | Khang, Tae Uk | - |
dc.contributor.author | Kang, Kyoung Hee | - |
dc.contributor.author | Song, Bong Keun | - |
dc.contributor.author | Park, Kyungmoon | - |
dc.contributor.author | Oh, Min-Kyu | - |
dc.contributor.author | Lee, Sang Yup | - |
dc.contributor.author | Park, Si Jae | - |
dc.date.accessioned | 2021-09-02T22:23:04Z | - |
dc.date.available | 2021-09-02T22:23:04Z | - |
dc.date.created | 2021-06-16 | - |
dc.date.issued | 2017-12 | - |
dc.identifier.issn | 0960-8524 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/81354 | - |
dc.description.abstract | This study examined nine expired industrial Corynebacterium glutamicum strains with high lysine producing capability for enhanced production of 5-AVA. C. glutamicum KCTC 1857 exhibiting the highest lysine production was transformed with either original Pseudomonas putida davBA genes, encoding the 5-AVA biosynthesis pathway, or C. glutamicum codon-optimized davBA genes. C. glutamicum KCTC 1857 expressing the original genes had superior cell viability and 5-AVA production capability compared to the other strain. This strain produced 39.93 g/L of 5-AVA, which is the highest titer reported to date in fed-batch fermentation from glucose. Indeed, Miscanthus hydrolysate solution prepared from a novel process, comprising pretreatment, hydrolysis, purification, and concentration, was used as feedstock for 5-AVA production. A total of 12.51 g/L 5-AVA was produced from the Miscanthus hydrolysate; this value is 34.7% higher than that obtained from glucose in batch fermentation. (C) 2017 Elsevier Ltd. All rights reserved. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCI LTD | - |
dc.subject | SUBSEQUENT ENZYMATIC-HYDROLYSIS | - |
dc.subject | HIGH-LEVEL CONVERSION | - |
dc.subject | ESCHERICHIA-COLI | - |
dc.subject | L-LYSINE | - |
dc.subject | CHEMICALS | - |
dc.subject | BIOMASS | - |
dc.subject | HYDROTHERMOLYSIS | - |
dc.subject | EXPRESSION | - |
dc.subject | CADAVERINE | - |
dc.subject | GLUTARATE | - |
dc.title | Production of 5-aminovaleric acid in recombinant Corynebacterium glutamicum strains from a Miscanthus hydrolysate solution prepared by a newly developed Miscanthus hydrolysis process | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Oh, Min-Kyu | - |
dc.identifier.doi | 10.1016/j.biortech.2017.05.131 | - |
dc.identifier.scopusid | 2-s2.0-85020107107 | - |
dc.identifier.wosid | 000413038300048 | - |
dc.identifier.bibliographicCitation | BIORESOURCE TECHNOLOGY, v.245, pp.1692 - 1700 | - |
dc.relation.isPartOf | BIORESOURCE TECHNOLOGY | - |
dc.citation.title | BIORESOURCE TECHNOLOGY | - |
dc.citation.volume | 245 | - |
dc.citation.startPage | 1692 | - |
dc.citation.endPage | 1700 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Agriculture | - |
dc.relation.journalResearchArea | Biotechnology & Applied Microbiology | - |
dc.relation.journalResearchArea | Energy & Fuels | - |
dc.relation.journalWebOfScienceCategory | Agricultural Engineering | - |
dc.relation.journalWebOfScienceCategory | Biotechnology & Applied Microbiology | - |
dc.relation.journalWebOfScienceCategory | Energy & Fuels | - |
dc.subject.keywordPlus | SUBSEQUENT ENZYMATIC-HYDROLYSIS | - |
dc.subject.keywordPlus | HIGH-LEVEL CONVERSION | - |
dc.subject.keywordPlus | ESCHERICHIA-COLI | - |
dc.subject.keywordPlus | L-LYSINE | - |
dc.subject.keywordPlus | CHEMICALS | - |
dc.subject.keywordPlus | BIOMASS | - |
dc.subject.keywordPlus | HYDROTHERMOLYSIS | - |
dc.subject.keywordPlus | EXPRESSION | - |
dc.subject.keywordPlus | CADAVERINE | - |
dc.subject.keywordPlus | GLUTARATE | - |
dc.subject.keywordAuthor | Corynebacterium glutamicum | - |
dc.subject.keywordAuthor | Metabolic engineering | - |
dc.subject.keywordAuthor | 5-Aminovaleric acid | - |
dc.subject.keywordAuthor | Miscanthus | - |
dc.subject.keywordAuthor | Pretreatment | - |
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