Neuroanatomical Mechanism of Cerebellar Mutism After Stroke
- Authors
- Lee, Sekwang; Na, Yoon Hye; Moon, Hyun Im; Tae, Woo Suk; Pyun, Sung-Bom
- Issue Date
- 12월-2017
- Publisher
- KOREAN ACAD REHABILITATION MEDICINE
- Keywords
- Akinetic mutism; Cerebellum; Diffusion tensor imaging
- Citation
- ANNALS OF REHABILITATION MEDICINE-ARM, v.41, no.6, pp.1076 - 1081
- Indexed
- SCOPUS
KCI
- Journal Title
- ANNALS OF REHABILITATION MEDICINE-ARM
- Volume
- 41
- Number
- 6
- Start Page
- 1076
- End Page
- 1081
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/81429
- DOI
- 10.5535/arm.2017.41.6.1076
- ISSN
- 2234-0645
- Abstract
- Cerebellar mutism (CM) is a rare neurological condition characterized by lack of speech due to cerebellar lesions. CM is often reported in children. We describe a rare case of CM after spontaneous cerebellar hemorrhage. The patient showed mutism, irritability, decreased spontaneous movements and oropharyngeal apraxia. Diffusion tensor imaging revealed significant volume reduction of medial frontal projection fibers from the corpus callosum. In Tracts Constrained by UnderLying Anatomy (TRACULA) analysis, forceps major and minor and bilateral cingulum-angular bundles were not visualized. Cerebello-frontal pathway reconstructed from the FMRIB Software Library showed continuity of fibers, with decreased number of fibers on qualitative analysis. These results suggest that cerebello-frontal disconnection may be a neuroanatomical mechanism of CM. Damage of brain network between occipital lobe, cingulate and cerebellum caused by hemorrhage may also have role in the mechanism of CM in our case.
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Collections - Graduate School > Department of Biomedical Sciences > 1. Journal Articles
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