Bilateral versus unilateral placement of metal stents for inoperable high-grade malignant hilar biliary strictures: a multicenter, prospective, randomized study (with video)
DC Field | Value | Language |
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dc.contributor.author | Lee, Tae Hoon | - |
dc.contributor.author | Kim, Tae Hyeon | - |
dc.contributor.author | Moon, Jong Ho | - |
dc.contributor.author | Lee, Sang Hyub | - |
dc.contributor.author | Choi, Hyun Jong | - |
dc.contributor.author | Hwangbo, Young | - |
dc.contributor.author | Hyun, Jong Jin | - |
dc.contributor.author | Choi, Jun-Ho | - |
dc.contributor.author | Jeong, Seok | - |
dc.contributor.author | Kim, Jong Hyeok | - |
dc.contributor.author | Park, Do Hyun | - |
dc.contributor.author | Han, Joung-Ho | - |
dc.contributor.author | Park, Sang-Heum | - |
dc.date.accessioned | 2021-09-03T00:00:31Z | - |
dc.date.available | 2021-09-03T00:00:31Z | - |
dc.date.created | 2021-06-18 | - |
dc.date.issued | 2017-11 | - |
dc.identifier.issn | 0016-5107 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/81849 | - |
dc.description.abstract | Background and Aims: The efficacy of palliative biliary drainage by using bilateral or unilateral self-expandable metal stents (SEMSs) for a malignant hilar biliary stricture (MHS) remains controversial. This prospective, randomized, multicenter study investigated whether bilateral drainage by using SEMSs is superior to unilateral drainage in patients with inoperable MHSs. Methods: Patients with inoperable high-grade MHSs who underwent palliative endoscopic insertion of bilateral or unilateral SEMSs were enrolled. The main outcome measurements were the rate of primary reintervention for malfunction after successful placement of SEMSs, stent patency, technical and clinical success rates, adverse events, and survival duration. Results: A total of 133 pathology-diagnosed patientswere randomized to the bilateral group (n=67) or the unilateral group (n=66). The primary technical success rates were 95.5%(64/67) and 100%(66/66) in the bilateral and unilateral groups, respectively (P = .244). The clinical success rates were 95.3% (61/64) and 84.9% (56/66), respectively (P Z.047). The primary reintervention rates based on the per-protocol analysis were 42.6% (26/61) in the bilateral group and 60.3% (38/63) in the unilateral group (P = .049). The median cumulative stent patency duration was 252 days in the bilateral group and 139 days in the unilateral group. The risk of stent patency failure was significantly higher in the unilateral group (log-rank test; P < .01). In a multivariate Cox proportional hazardmodel to assess stent patency, bilateral SEMS placement was a favorable factor (adjusted hazard ratio 0.30, 95% confidence interval, 0.172-0.521; P <.001). Survival probability and late adverse events were not different between the 2 groups. Conclusions: Unilateral and bilateral drainage strategies by using SEMSs had similar technical success rates, but bilateral drainage resulted in fewer reinterventions and more durable stent patency in patients with inoperable high-grade MHSs. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | MOSBY-ELSEVIER | - |
dc.subject | HEPATIC DUCT DRAINAGE | - |
dc.subject | SIDE-BY-SIDE | - |
dc.subject | ENDOPROSTHESIS INSERTION | - |
dc.subject | SURGICAL-MANAGEMENT | - |
dc.subject | REVISION EFFICACY | - |
dc.subject | PLASTIC STENTS | - |
dc.subject | OBSTRUCTION | - |
dc.subject | CHOLANGIOCARCINOMA | - |
dc.subject | PALLIATION | - |
dc.subject | DEPLOYMENT | - |
dc.title | Bilateral versus unilateral placement of metal stents for inoperable high-grade malignant hilar biliary strictures: a multicenter, prospective, randomized study (with video) | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Hyun, Jong Jin | - |
dc.identifier.doi | 10.1016/j.gie.2017.04.037 | - |
dc.identifier.scopusid | 2-s2.0-85020743935 | - |
dc.identifier.wosid | 000413305600006 | - |
dc.identifier.bibliographicCitation | GASTROINTESTINAL ENDOSCOPY, v.86, no.5, pp.817 - 827 | - |
dc.relation.isPartOf | GASTROINTESTINAL ENDOSCOPY | - |
dc.citation.title | GASTROINTESTINAL ENDOSCOPY | - |
dc.citation.volume | 86 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 817 | - |
dc.citation.endPage | 827 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Gastroenterology & Hepatology | - |
dc.relation.journalWebOfScienceCategory | Gastroenterology & Hepatology | - |
dc.subject.keywordPlus | HEPATIC DUCT DRAINAGE | - |
dc.subject.keywordPlus | SIDE-BY-SIDE | - |
dc.subject.keywordPlus | ENDOPROSTHESIS INSERTION | - |
dc.subject.keywordPlus | SURGICAL-MANAGEMENT | - |
dc.subject.keywordPlus | REVISION EFFICACY | - |
dc.subject.keywordPlus | PLASTIC STENTS | - |
dc.subject.keywordPlus | OBSTRUCTION | - |
dc.subject.keywordPlus | CHOLANGIOCARCINOMA | - |
dc.subject.keywordPlus | PALLIATION | - |
dc.subject.keywordPlus | DEPLOYMENT | - |
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