Current status and future direction of biodegradable metallic and polymeric vascular scaffolds for next-generation stents
- Authors
- Im, Seung Hyuk; Jung, Youngmee; Kim, Soo Hyun
- Issue Date
- 15-9월-2017
- Publisher
- ELSEVIER SCI LTD
- Keywords
- Coronary artery disease; Cardiovascular stents; Biodegradable metallic scaffolds; Biodegradable polymeric scaffolds; Next-generation stents
- Citation
- ACTA BIOMATERIALIA, v.60, pp.3 - 22
- Indexed
- SCIE
SCOPUS
- Journal Title
- ACTA BIOMATERIALIA
- Volume
- 60
- Start Page
- 3
- End Page
- 22
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/82226
- DOI
- 10.1016/j.actbio.2017.07.019
- ISSN
- 1742-7061
- Abstract
- Because of the increasing incidence of coronary artery disease, the importance of cardiovascular stents has continuously increased as a treatment of this disease. Biodegradable scaffolds fabricated from polymers and metals have emerged as promising materials for vascular stents because of their biodegradability. Although such stent framework materials have shown good clinical efficacy, it is difficult to decide whether polymers or metals are better vascular scaffolds because their properties are different. Therefore, there are still obstacles in the development of biodegradable vascular scaffolds in terms of improving clinical efficacy. This review analyzes the pros and cons of current stent materials with respect to five key factors for next-generation stent and discusses methods of improvement. Furthermore, we discuss biodegradable electronic stents with electrical conductivity, which has been considered unimportant until now, and highlight electrical conductivity as a key factor in the development of next-generation stents. (C) 2017 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.
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Collections - Graduate School > KU-KIST Graduate School of Converging Science and Technology > 1. Journal Articles
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