Effect of processing method on platycodin D content in Platycodon grandiflorum roots
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kwon, Jaeyoung | - |
dc.contributor.author | Lee, Hyaemin | - |
dc.contributor.author | Kim, Nahyun | - |
dc.contributor.author | Lee, Je-Hyun | - |
dc.contributor.author | Woo, Mi Hee | - |
dc.contributor.author | Kim, Jinwoong | - |
dc.contributor.author | Kim, Yeong Shik | - |
dc.contributor.author | Lee, Dongho | - |
dc.date.accessioned | 2021-09-03T02:18:35Z | - |
dc.date.available | 2021-09-03T02:18:35Z | - |
dc.date.created | 2021-06-16 | - |
dc.date.issued | 2017-09 | - |
dc.identifier.issn | 0253-6269 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/82389 | - |
dc.description.abstract | Platycodon grandiflorum root is a traditional medicine and food material rich in triterpenoid saponins. Its major constituent, platycodin D (PD), is known to have various pharmacological properties, but processing methods may influence the PD content. In this study, a fully validated HPLC-ELSD method was developed for the quantification of PD in various states of 73 P. grandiflorum root samples from East Asia, and it exhibited a marked variation of the content. Furthermore, the effects of processing procedures such as peeling and drying temperature on the PD content were investigated using UPLC-ELSD analysis, and as a result, a significant influence of processing methods such as peeling and heating of samples on the content was confirmed. Specifically, unpeeled samples that were dried at 40 A degrees C showed the greatest PD content. The obtained results could facilitate the reliable standardization of P. grandiflorum for precise authentication and efficacious applications. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | PHARMACEUTICAL SOC KOREA | - |
dc.subject | SAPONINS | - |
dc.subject | PATHWAY | - |
dc.subject | CELLS | - |
dc.subject | MICE | - |
dc.title | Effect of processing method on platycodin D content in Platycodon grandiflorum roots | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lee, Dongho | - |
dc.identifier.doi | 10.1007/s12272-017-0946-6 | - |
dc.identifier.scopusid | 2-s2.0-85028745242 | - |
dc.identifier.wosid | 000411863500008 | - |
dc.identifier.bibliographicCitation | ARCHIVES OF PHARMACAL RESEARCH, v.40, no.9, pp.1087 - 1093 | - |
dc.relation.isPartOf | ARCHIVES OF PHARMACAL RESEARCH | - |
dc.citation.title | ARCHIVES OF PHARMACAL RESEARCH | - |
dc.citation.volume | 40 | - |
dc.citation.number | 9 | - |
dc.citation.startPage | 1087 | - |
dc.citation.endPage | 1093 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART002263793 | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Medicinal | - |
dc.relation.journalWebOfScienceCategory | Pharmacology & Pharmacy | - |
dc.subject.keywordPlus | SAPONINS | - |
dc.subject.keywordPlus | PATHWAY | - |
dc.subject.keywordPlus | CELLS | - |
dc.subject.keywordPlus | MICE | - |
dc.subject.keywordAuthor | Platycodon grandiflorum | - |
dc.subject.keywordAuthor | Platycodi Radix | - |
dc.subject.keywordAuthor | Platycodin D | - |
dc.subject.keywordAuthor | HPLC-ELSD | - |
dc.subject.keywordAuthor | Processing method | - |
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