Structural diversity of marine cyclic peptides and their molecular mechanisms for anticancer, antibacterial, antifungal, and other clinical applications
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, Yeji | - |
dc.contributor.author | Phat, Chanvorleak | - |
dc.contributor.author | Hong, Soon-Cheol | - |
dc.date.accessioned | 2021-09-03T02:39:53Z | - |
dc.date.available | 2021-09-03T02:39:53Z | - |
dc.date.created | 2021-06-16 | - |
dc.date.issued | 2017-09 | - |
dc.identifier.issn | 0196-9781 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/82479 | - |
dc.description.abstract | Many cyclic peptides and analogues derived from marine sources are known to possess biological properties, including anticancer, antitumor, antibacterial, antifungal, antiparasitic, anti-inflammation, anti-proliferative, anti-hypertensive, cytotoxic, and antibiotic properties. These compounds demonstrate different activities and modes of action according to their structure such as cyclic oligopeptide, cyclic lipopeptide, cyclic glycopeptide and cyclic depsipeptide. The recent advances in application of the above-mentioned cyclic peptides were reported in dolastatins, soblidotin, didemnin B, aplidine, salinosporamide A, kahalalide F and bryostatin 1 and they are currently in clinical trials. These cyclic peptides are possible novel drugs discovered and developed from marine origin. Literature data concerning the potential properties of marine cyclic peptides were reviewed here, and the structural diversity and biological activities of marine cyclic peptides are discussed in relation to the molecular mechanisms of these marine cyclic peptides. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCIENCE INC | - |
dc.subject | NEW-GUINEA COLLECTION | - |
dc.subject | A-C | - |
dc.subject | KAHALALIDE-F | - |
dc.subject | BIOACTIVE PEPTIDES | - |
dc.subject | PHASE-I | - |
dc.subject | CYTOTOXIC DEPSIPEPTIDES | - |
dc.subject | POTENTIAL SOURCES | - |
dc.subject | NATURAL-PRODUCTS | - |
dc.subject | DOLASTATIN 10 | - |
dc.subject | KAPPA-B | - |
dc.title | Structural diversity of marine cyclic peptides and their molecular mechanisms for anticancer, antibacterial, antifungal, and other clinical applications | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Hong, Soon-Cheol | - |
dc.identifier.doi | 10.1016/j.peptides.2017.06.002 | - |
dc.identifier.scopusid | 2-s2.0-85026821585 | - |
dc.identifier.wosid | 000410016800013 | - |
dc.identifier.bibliographicCitation | PEPTIDES, v.95, pp.94 - 105 | - |
dc.relation.isPartOf | PEPTIDES | - |
dc.citation.title | PEPTIDES | - |
dc.citation.volume | 95 | - |
dc.citation.startPage | 94 | - |
dc.citation.endPage | 105 | - |
dc.type.rims | ART | - |
dc.type.docType | Review | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Endocrinology & Metabolism | - |
dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
dc.relation.journalWebOfScienceCategory | Endocrinology & Metabolism | - |
dc.relation.journalWebOfScienceCategory | Pharmacology & Pharmacy | - |
dc.subject.keywordPlus | NEW-GUINEA COLLECTION | - |
dc.subject.keywordPlus | A-C | - |
dc.subject.keywordPlus | KAHALALIDE-F | - |
dc.subject.keywordPlus | BIOACTIVE PEPTIDES | - |
dc.subject.keywordPlus | PHASE-I | - |
dc.subject.keywordPlus | CYTOTOXIC DEPSIPEPTIDES | - |
dc.subject.keywordPlus | POTENTIAL SOURCES | - |
dc.subject.keywordPlus | NATURAL-PRODUCTS | - |
dc.subject.keywordPlus | DOLASTATIN 10 | - |
dc.subject.keywordPlus | KAPPA-B | - |
dc.subject.keywordAuthor | Cyclic peptides | - |
dc.subject.keywordAuthor | Marine organism | - |
dc.subject.keywordAuthor | Anticancer | - |
dc.subject.keywordAuthor | Antibacterial | - |
dc.subject.keywordAuthor | Antifungal | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(02841) 서울특별시 성북구 안암로 14502-3290-1114
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.