Effect of arabinoxylan- and rhamnogalacturonan I-rich polysaccharides isolated from young barley leaf on intestinal immunostimulatory activity
DC Field | Value | Language |
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dc.contributor.author | Kim, Hoon | - |
dc.contributor.author | Yu, Kwang-Won | - |
dc.contributor.author | Hong, Hee-Do | - |
dc.contributor.author | Shin, Kwang-Soon | - |
dc.date.accessioned | 2021-09-03T03:21:32Z | - |
dc.date.available | 2021-09-03T03:21:32Z | - |
dc.date.created | 2021-06-16 | - |
dc.date.issued | 2017-08 | - |
dc.identifier.issn | 1756-4646 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/82652 | - |
dc.description.abstract | Four polysaccharide fractions were prepared from barley leaves and then in vitro intestinal immunostimulatory activity was compared. Among fractions, high molecular weight fraction prepared by enzyme extraction, namely BLE-P, showed the potent in activating bone marrow cell proliferation through Peyer's patch (PP), and in stimulating cytokine production in in vitro. By performing monosaccharide composition analysis, BLE-P was identified as a mixture of hemicellulosic glucuronoarabinoxylan and pectic rhamnogalacturonan I accounting for above 80%. Subsequently, BLE-P was orally administered to mice for 20 days to investigate the effect on the in vivo intestinal immunostimulatory activity. BLE-P administration not only augmented the production of immunoglobulin A (IgA), but also increased the levels of IgA-related cytokines, such as transforming growth factor-beta and interleukin-10. These results suggest that BLE-P is most likely to facilitate the production of IgA via induction of various IgA-producing cytokines in small intestinal immune system. (C) 2017 Elsevier Ltd. All rights reserved. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCIENCE BV | - |
dc.title | Effect of arabinoxylan- and rhamnogalacturonan I-rich polysaccharides isolated from young barley leaf on intestinal immunostimulatory activity | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Hoon | - |
dc.identifier.doi | 10.1016/j.jff.2017.05.052 | - |
dc.identifier.scopusid | 2-s2.0-85020245699 | - |
dc.identifier.wosid | 000406080900041 | - |
dc.identifier.bibliographicCitation | JOURNAL OF FUNCTIONAL FOODS, v.35, pp.384 - 390 | - |
dc.relation.isPartOf | JOURNAL OF FUNCTIONAL FOODS | - |
dc.citation.title | JOURNAL OF FUNCTIONAL FOODS | - |
dc.citation.volume | 35 | - |
dc.citation.startPage | 384 | - |
dc.citation.endPage | 390 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Food Science & Technology | - |
dc.relation.journalResearchArea | Nutrition & Dietetics | - |
dc.relation.journalWebOfScienceCategory | Food Science & Technology | - |
dc.relation.journalWebOfScienceCategory | Nutrition & Dietetics | - |
dc.subject.keywordAuthor | Barley leaf | - |
dc.subject.keywordAuthor | Intestinal immune system | - |
dc.subject.keywordAuthor | Immunoglobulin A | - |
dc.subject.keywordAuthor | Peyer&apos | - |
dc.subject.keywordAuthor | s patch | - |
dc.subject.keywordAuthor | Polysaccharide | - |
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